Evidence supporting the use of: Grindelia
For the health condition: Cough (spastic)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Grindelia, commonly known as gumweed, has a long history of traditional use for respiratory conditions, including spastic (or convulsive) coughs. Indigenous peoples of North America and later European settlers used Grindelia species as a remedy for bronchial irritation, asthma, and persistent coughs. The plant contains resinous compounds, flavonoids, and saponins, which are thought to contribute to its expectorant and mild antispasmodic effects. Traditional herbal texts and pharmacopeias from the 19th and early 20th centuries document its use for soothing irritated mucous membranes and reducing bronchial spasm, making it a common ingredient in cough syrups of that era.
However, while these uses are well-recorded in ethnobotanical and early medical literature, modern clinical trials or robust pharmacological studies specifically validating Grindelia for spastic cough are limited. There are some in vitro and animal studies showing mild relaxant effects on smooth muscle and anti-inflammatory properties, but these do not constitute strong scientific evidence for efficacy in humans. As such, the justification for its use in spastic cough is primarily traditional, with only weak supportive evidence from preclinical research.
Other ingredients used for Cough (spastic)
aloe veraalpha-pinene
apple
waterhyssop
benegut perilla (proprietary)
beta-pinene
black cumin
black currant
black pepper
Indian frankincense
cat's claw
chen pi
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
garlic bulb
ginger
glehnia root
grape
greek mountain tea
onion
green tea
heartwood
Indian tinospora
jujube
lemon
licorice root
lovage
nettle
ophiopogon root
orange
pear
platycodon root
plum fruit
pomegranate
spearmint leaf
sphaeranthus indicus
thyme
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
lobelia
capsicum
Indian bael
malabar nut
alpinia galangal
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
punarnava
prickly ash
fritillaria
yerba santa
elecampane
coltsfoot
juniper berries
dodder
sweet flag
eucalyptus
abies spectabilis
horehound
soursop
Alcohol
Aralia
Agastache
Anamarrhena
Alpha-terpineol
Ambergris
acacia
Allicin
Asarum heterotropoides
Albizia
Aconite
Asafoetida
Andrographolide
Aerva lanata
Asam gelugor
Andrographis
Allyl Sulfide
Adenophora
Allium tuberosum
Aniseed myrtle
Asarum sieboldii
Alantolactone
Atractylone
Black Seed
Bayleaf
Baccharoides anthelmintica
black salt
Buddha's Hand
Borage
Balloon Flower
Belamcanda
Bergenia
Cnidium
Cactus
Citron
Citrus
Cineole
Capsaicin
Cistus
Cubeb
Cowslip
Calamus
Cyanthillium cinereum
Cinnamaldehyde
Costus
Chekiang Fritillary
Chondrus
Dragonhead
Diterpenes
Dichrostachys glomerata
Echinacea
Ephedrine
Galangal
Ivy
Poppy
Other health conditions supported by Grindelia
AsthmaBronchitis
Cough (damp)
Cough (general)
Cough (spastic)
Inflammation