Evidence supporting the use of: Horehound
For the health condition: Cough (spastic)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Horehound (Marrubium vulgare) has a long history of traditional use as a remedy for coughs, including spastic (or spasmodic) coughs. It has been used in various forms—teas, syrups, and lozenges—in European folk medicine for centuries. The plant contains bitter principles, such as marrubiin, which are believed to stimulate the secretion of bronchial mucus, thereby soothing irritated respiratory passages and helping to reduce the cough reflex. Historical texts and pharmacopeias have listed horehound as an expectorant and antitussive (cough suppressant) since at least the Middle Ages.

However, while horehound’s use is well-documented in traditional medicine, scientific validation remains limited. A few in vitro and animal studies suggest marrubiin may have mild expectorant and antispasmodic effects, but robust clinical trials in humans are lacking. Systematic reviews and authoritative sources, such as the European Medicines Agency (EMA) and the German Commission E, acknowledge its traditional use for cough but also note the insufficient scientific evidence to confirm efficacy. Thus, while horehound is still found in some cough remedies and herbal preparations, its use for spastic cough is primarily justified by tradition rather than strong scientific backing.

In summary, horehound’s reputation for relieving cough—especially spastic cough—rests mainly on historical and traditional use rather than conclusive modern research.

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