Evidence supporting the use of: Horehound
For the health condition: Cough (spastic)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Horehound (Marrubium vulgare) has a long history of traditional use as a remedy for coughs, including spastic (or spasmodic) coughs. It has been used in various forms—teas, syrups, and lozenges—in European folk medicine for centuries. The plant contains bitter principles, such as marrubiin, which are believed to stimulate the secretion of bronchial mucus, thereby soothing irritated respiratory passages and helping to reduce the cough reflex. Historical texts and pharmacopeias have listed horehound as an expectorant and antitussive (cough suppressant) since at least the Middle Ages.
However, while horehound’s use is well-documented in traditional medicine, scientific validation remains limited. A few in vitro and animal studies suggest marrubiin may have mild expectorant and antispasmodic effects, but robust clinical trials in humans are lacking. Systematic reviews and authoritative sources, such as the European Medicines Agency (EMA) and the German Commission E, acknowledge its traditional use for cough but also note the insufficient scientific evidence to confirm efficacy. Thus, while horehound is still found in some cough remedies and herbal preparations, its use for spastic cough is primarily justified by tradition rather than strong scientific backing.
In summary, horehound’s reputation for relieving cough—especially spastic cough—rests mainly on historical and traditional use rather than conclusive modern research.
Other ingredients used for Cough (spastic)
aloe veraalpha-pinene
apple
waterhyssop
benegut perilla (proprietary)
beta-pinene
black cumin
black currant
black pepper
Indian frankincense
cat's claw
chen pi
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
garlic bulb
ginger
glehnia root
grape
greek mountain tea
onion
green tea
heartwood
Indian tinospora
jujube
lemon
licorice root
lovage
nettle
ophiopogon root
orange
pear
platycodon root
plum fruit
pomegranate
spearmint leaf
sphaeranthus indicus
thyme
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
lobelia
capsicum
Indian bael
malabar nut
alpinia galangal
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
punarnava
prickly ash
fritillaria
yerba santa
elecampane
coltsfoot
juniper berries
dodder
sweet flag
eucalyptus
abies spectabilis
horehound
soursop
Alcohol
Aralia
Agastache
Anamarrhena
Alpha-terpineol
Ambergris
acacia
Allicin
Asarum heterotropoides
Albizia
Aconite
Asafoetida
Andrographolide
Aerva lanata
Asam gelugor
Andrographis
Allyl Sulfide
Adenophora
Allium tuberosum
Aniseed myrtle
Asarum sieboldii
Alantolactone
Atractylone
Black Seed
Bayleaf
Baccharoides anthelmintica
black salt
Buddha's Hand
Borage
Balloon Flower
Belamcanda
Bergenia
Cnidium
Cactus
Citron
Citrus
Cineole
Capsaicin
Cistus
Cubeb
Cowslip
Calamus
Cyanthillium cinereum
Cinnamaldehyde
Costus
Chekiang Fritillary
Chondrus
Dragonhead
Diterpenes
Dichrostachys glomerata
Echinacea
Ephedrine
Galangal
Ivy
Poppy
Other health conditions supported by horehound
Acid IndigestionAsthma
Bronchitis
Colds (decongestant)
Colds (general)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Cough (damp)
Cough (general)
Cough (spastic)
Digestion (poor)
Emphysema
Gas and Bloating
Indigestion
Inflammation
Laryngitis
Nausea and Vomiting
Sore Throat
Sweat Baths (herbs for)
Wheezing
Wounds and Sores