Evidence supporting the use of: Khella
For the health condition: Cough (spastic)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Khella (Ammi visnaga) has a long-standing history of use in traditional medicine, particularly in the Mediterranean and Middle Eastern regions, for respiratory conditions such as spastic cough, asthma, and bronchitis. The plant's fruits contain active compounds like khellin and visnagin, which have been reported to possess smooth muscle relaxant and bronchodilatory effects. Historical texts and ethnobotanical surveys document that herbalists and practitioners used Khella extracts as a remedy for spasmodic coughs and bronchial constriction, often relying on its ability to relax airway smooth muscles and alleviate symptoms. However, robust clinical data are lacking, and most evidence is derived from traditional usage or preclinical studies rather than rigorous human trials. Modern phytotherapy references sometimes mention Khella for cough and bronchospasm based on its antispasmodic properties, but scientific validation is limited, and safety concerns (such as phototoxicity and potential toxicity at high doses) restrict its widespread use. Therefore, while there is a traditional basis and some pharmacological rationale, substantial scientific validation and clinical trials supporting its effectiveness for spastic cough are insufficient.

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