Evidence supporting the use of: Licorice (various)
For the health condition: Cough (spastic)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Licorice (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, such as Traditional Chinese Medicine (TCM) and Ayurveda, for the treatment of coughs, including spastic (dry, irritating) cough. In these traditions, licorice root is valued for its demulcent (soothing), expectorant, and anti-inflammatory properties. Classic texts often mention licorice in cough syrups and decoctions, either as a primary or supportive ingredient, intended to soothe irritated mucous membranes of the throat and airways.

Modern scientific investigations confirm that licorice contains glycyrrhizin and other saponins, which exhibit anti-inflammatory and mild expectorant effects in laboratory studies. Some small clinical studies and animal experiments suggest that licorice extracts can reduce cough frequency and soothe airway irritation, likely due to their mucoprotective and anti-inflammatory actions. However, robust, large-scale clinical trials specifically evaluating licorice for spastic cough in humans are lacking. Most available evidence is either preclinical or from traditional use, with only limited human data. Safety concerns also exist with prolonged use or high doses, due to potential side effects such as hypertension and hypokalemia.

Overall, the use of licorice for spastic cough is primarily based on traditional and historical evidence, with some supportive but limited scientific data. It remains a common component in herbal cough remedies globally, but more rigorous clinical studies are needed to fully validate its efficacy and safety for this indication.

More about Licorice (various)
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