Polygonatum cirrhifolium (commonly known as curly-leaved Solomon’s seal) has been used in traditional medicine systems, particularly in parts of the Himalayas and traditional Chinese medicine, for the treatment of various respiratory ailments, including coughs. The roots and rhizomes are the primary parts used and are believed to possess demulcent and expectorant properties, which can help soothe irritated mucous membranes and support relief from cough, especially spastic or dry coughs.

Ethnobotanical surveys and traditional medicinal texts document its use for cough, asthma, and bronchial issues, often administered as decoctions or powders. However, while these uses are well-recorded in traditional settings, there is a lack of robust, peer-reviewed scientific studies directly validating its efficacy for spastic cough. Most available data are anecdotal or based on traditional knowledge without controlled clinical trials.

Some phytochemical studies indicate the plant contains saponins, flavonoids, and polysaccharides, which may theoretically have soothing or anti-inflammatory effects on the respiratory tract, but these findings are preliminary and not specifically tied to clinical outcomes for cough. Therefore, while its use is justified by tradition, scientific evidence remains limited, and further research would be necessary to confirm its specific role in treating spastic cough.