Evidence supporting the use of: Thymoquinone
For the health condition: Cough (spastic)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Thymoquinone is a bioactive compound found in the volatile oil of Nigella sativa (black seed), a traditional medicinal plant. The use of black seed and its derivatives for treating coughs and other respiratory ailments has roots in traditional medicine, particularly within Middle Eastern and South Asian cultures. Historical texts and ethnobotanical surveys document the use of Nigella sativa seeds and oil for "spastic" or persistent coughs, often as part of polyherbal remedies or in decoctions.

Scientific evidence directly supporting the use of thymoquinone itself for spastic cough is limited and mostly preclinical. Some animal studies have shown that thymoquinone possesses anti-inflammatory and bronchodilatory properties, which may theoretically help alleviate cough severity. For example, studies in rodents have demonstrated a reduction in airway inflammation and hyperreactivity with thymoquinone administration. There is also some evidence of antitussive (cough-suppressing) effects of Nigella sativa oil in animal models, but very few clinical trials have evaluated thymoquinone or black seed in humans specifically for cough.

Overall, the use of thymoquinone for spastic cough is primarily justified by traditional use, with limited and indirect scientific support. The evidence is mostly based on historical use and preclinical studies, with a lack of robust clinical trials in humans for this indication.

More about Thymoquinone
More about Cough (spastic)

Products containing Thymoquinone

We currently have no products on Vitabase that contain this ingredient.