Evidence supporting the use of: Vasicine
For the health condition: Cough (spastic)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Vasicine is a quinazoline alkaloid derived from the plant Adhatoda vasica (also known as Malabar nut), which has been traditionally used in Ayurvedic and Unani medicine systems for the treatment of respiratory conditions, especially cough and asthma. The use of Vasicine for cough (including spastic cough) is not only rooted in tradition but also supported by scientific studies. Pharmacological research has shown that Vasicine exhibits bronchodilatory, expectorant, and antitussive (cough-suppressing) activities. In vitro and in vivo studies on animal models have demonstrated that Vasicine can relax bronchial smooth muscles, leading to improved airflow and reduction of bronchospasms. It also promotes the expulsion of mucus from the airways, which helps relieve productive coughs. Some studies have compared the efficacy of Vasicine and its derivatives with standard bronchodilators and antitussives, finding comparable or additive effects.
Despite these findings, the majority of evidence comes from preclinical studies, with limited controlled clinical trials in humans. However, its traditional use and the pharmacological basis for its effects give moderate scientific support for its use in spastic cough and other respiratory ailments. Therefore, Vasicine's use for treating cough, particularly of spastic or asthmatic origin, is justified by both tradition and scientific research, though higher-quality human clinical trials are still needed to establish definitive efficacy and safety profiles.
Other ingredients used for Cough (spastic)
Abies spectabilisAcacia
Aconite
Adenophora
Aerva lanata
Agastache
Alantolactone
Albizia
Alcohol
Allicin
Allium tuberosum
Allyl sulfide
Aloe vera
alpha-pinene
alpha-terpineol
alpinia galangal
ambergris
Anamarrhena
Andrographis
andrographolide
anise
Aniseed myrtle
apple
Aralia
asafoetida
Asam gelugor
Asarum heterotropoides
Asarum sieboldii
atractylodes
atractylone
Baccharoides anthelmintica
balloon flower
bayleaf
Belamcanda
benegut perilla (proprietary)
Bergenia
beta-pinene
black cumin
black currant
black pepper
black salt
black seed
boneset
borage
Buddha\'s hand
cactus
calamus
capsaicin
capsicum
cat's claw
Chekiang Fritillary
chen pi
Chinese salvia root
Chondrus
cineole
cinnamaldehyde
cinnamon
Cistus
citron
Citrus
clove
Cnidium
coltsfoot
costus
cowage seed
cowslip
cubeb
Cyanthillium cinereum
Dichrostachys glomerata
diterpenes
dodder
dragonhead
Echinacea
elderberry
elecampane
ephedrine
eucalyptus
fernbush
flavoglycosides
fritillaria
fritillary
Galangal
Gallesia
garlic bulb
ginger
Glehnia littoralis
glehnia root
Glycyrrhetinic acid
Glycyrrhizin
grape
Greek mountain tea
green tea
Grindelia
Guaco
Guava
gum
heartwood
Hedychium spicatum
honey
honey loquat syrup
horehound
hyssop
Ilex
Indian bael
Indian frankincense
Indian tinospora
inula racemosa
Ivy
Japanese kadsura
Jatoba
Javanese Long Pepper
jujube
juniper berries
Khella
Lactucarium
Large-leaved linden
lemon
licorice root
Ligusticum
linden
Lindera
lobelia
loquat
Loranthus
lovage
lungwort
mace
madder
Maidenhair Fern
malabar nut
Marsh Tea
Meadow sage
Melia
Mentha haplocalyx
Mucilage
Mullein
Nettle
Nigella seed
Nutmeg
Nymphaea nouchali
onion
Ophiopogon
ophiopogon root
orange
Oroxylum indicum
Osha
Osmanthus
Paris polyphylla
pear
Pelargonium
Pimpinella
Pinellia ternata
Piper chaba
Piper retrofractum
pistacia integerrima gall
Platycodon
platycodon root
plum fruit
Polygala
Polypodium
pomegranate
poppy
prepared aconite tuber
prickly ash
punarnava
Pyrrosia
ravinsara
Rhododendron
Sabadilla
sarsaparilla
Sete sangrias
Shogaol
soursop
spearmint leaf
Sphaeranthus indicus
Stemona
sweet flag
Tea
Terpenoids
Theobromine
thyme
Thymoquinone
turmeric
Varuna
Vasicine
Vasicinol
Vasicinone
Vladimiria souliei
Waterhyssop
Yerba buena
Yerba santa
Zedoary
zhejiang fritillary
Zinc
Zingerone