Evidence supporting the use of: Angelica
For the health condition: Cramps and Spasms

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Angelica (particularly Angelica archangelica and Angelica sinensis, also known as Dong Quai) has a long history of use in traditional herbal medicine systems for the management of cramps and spasms, especially those associated with menstruation. In Traditional Chinese Medicine (TCM), Dong Quai is renowned as a "female tonic" and is commonly prescribed to alleviate menstrual discomfort, including cramps and spasmodic pain. Similarly, European folk medicine has used Angelica root for digestive and muscle cramps. The proposed mechanisms in traditional texts often cite its warming qualities and its ability to "move the blood" or relax smooth muscle tissue.

However, the scientific evidence supporting these uses is limited and generally of low quality. Some laboratory and animal studies suggest that Angelica extracts may have mild antispasmodic and muscle-relaxing properties, possibly due to the presence of compounds such as ligustilide. Nonetheless, clinical trials in humans are sparse, often methodologically weak, and results are inconsistent. Reviews and authoritative sources such as the European Medicines Agency and Natural Medicines Comprehensive Database note the lack of rigorous clinical validation for Angelica’s use in treating cramps or spasms.

In summary, Angelica’s use for cramps and spasms is supported primarily by a strong tradition in several herbal medicine systems, but scientific validation is limited. Evidence rating: 2 (weak traditional support, minimal scientific evidence).

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