Evidence supporting the use of: Boswellia serrata
For the health condition: Crohn's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Boswellia serrata, also known as Indian frankincense, has a history of use in traditional medicine for inflammatory conditions, but its application in Crohn’s Disease is primarily supported by some scientific evidence. The resin contains boswellic acids, which are thought to inhibit 5-lipoxygenase and reduce leukotriene synthesis, thus exerting anti-inflammatory effects. Several small-scale, randomized controlled trials have investigated Boswellia’s efficacy in inflammatory bowel diseases, including Crohn’s Disease and ulcerative colitis.

One notable study (Gerhardt et al., 2001, European Journal of Medical Research) compared Boswellia extract to mesalazine in maintaining remission of Crohn’s Disease. The study found that Boswellia was comparable to mesalazine in terms of efficacy, with 59% of the Boswellia group maintaining remission versus 55% in the mesalazine group. However, these studies are generally limited by small sample sizes, short durations, and varying product quality.

Systematic reviews (such as Langmead & Rampton, 2006, Alimentary Pharmacology & Therapeutics) conclude that while there is preliminary evidence suggesting benefit, larger, high-quality studies are needed before Boswellia can be routinely recommended for Crohn’s Disease. The safety profile appears favorable in the short term, but long-term safety is not well established.

In summary, the use of Boswellia serrata for Crohn’s Disease has limited but promising scientific support, warranting further research but not yet confirming it as a standard treatment option.

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