Evidence supporting the use of: Marijuana
For the health condition: Crohn's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Marijuana (cannabis) has been explored as a supportive therapy for Crohn's Disease due to its anti-inflammatory and immunomodulatory properties primarily mediated through the endocannabinoid system. Some patients report symptomatic relief, especially in terms of pain, appetite, and quality of life. However, the scientific evidence for its efficacy in treating the underlying inflammation of Crohn’s Disease is limited and mixed. A small double-blind, placebo-controlled study published in Clinical Gastroenterology and Hepatology (Naftali et al., 2013) found that inhaled cannabis improved symptoms but did not induce clinical remission. A 2021 review in Alimentary Pharmacology & Therapeutics concluded that while cannabis may improve patient-reported symptoms, it does not appear to reduce inflammation or lead to sustained remission. Most available studies are small, short-term, and have methodological limitations. Guidelines from organizations such as the American Gastroenterological Association do not recommend cannabis as a primary treatment for Crohn's Disease due to insufficient high-quality evidence. Overall, while there is some scientific investigation into cannabis for Crohn’s, current evidence does not strongly support its use for modifying disease activity, but it may help with symptom management in select patients.
Other ingredients used for Crohn's Disease
aloe veraanthocyanins
bacillus coagulans
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
turmeric
curcumin
fiber blend (proprietary)
fructooligosaccharides (FOS)
ginger
green tea
inulin
lactiplantibacillus plantarum
lactobacillus reuteri
lactococcus lactis
lactoferrin
licorice root
n-acetyl-cysteine (NAC)
phytocannabinoids
pomegranate
prebiotic blend (proprietary)
butyric acid
psyllium
quercetin
resveratrol
saccharomyces boulardii
specialized pro-resolving mediators (SPMs)
tributyrin
triphala
vitamin D
zinc
trace minerals
Bifidobacterium
Bifidobacterium adolescentis
Boswellic Acid
Bael
Boswellia
Bacteria
Bifidobacteria
Curcuminoid
Curcuma
Cannabidiol
Clostridium butyricum
Cannabigerol
Fiber
Other health conditions supported by Marijuana
Abdominal PainAcquired Immune Deficiency Syndrome
Alzheimer's Disease
Anxiety
Anxiety Disorders
Appetite (deficient)
Arthritis
Asthma
Backache
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Colitis
Convalescence
Convulsions
Crohn's Disease
Depression
Epilepsy
Glaucoma