Evidence supporting the use of: Protein (unspecified)
For the health condition: Crohn's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Protein (unspecified) is scientifically validated as an important nutritional support in Crohn's Disease management. Crohn's Disease often leads to malnutrition, weight loss, and muscle wasting due to chronic inflammation, reduced appetite, malabsorption, and increased metabolic demands. Several clinical guidelines, including those from organizations such as the European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN), recommend ensuring adequate protein intake in patients with Crohn's Disease, especially during active disease or recovery from flares and surgery. Increased protein needs (often 1.2–1.5 g/kg/day) are typically suggested to help restore and maintain lean body mass, promote wound healing, and support immune function. While protein supplementation alone does not treat the underlying inflammation of Crohn's Disease, it plays a crucial role in addressing secondary complications related to malnutrition. Evidence for the benefit of protein supplementation is especially strong in pediatric Crohn's patients, where exclusive enteral nutrition (liquid formula diets high in protein and calories) can induce remission and support growth. Overall, while protein is not a disease-modifying therapy, its use as nutritional support is well-supported by clinical evidence and forms part of the standard care for individuals with Crohn's Disease at risk of malnutrition.

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