Evidence supporting the use of: Resistant Starch
For the health condition: Crohn's Disease

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Resistant starch (RS) has attracted scientific interest for its potential role in managing Crohn's Disease, although the evidence is still preliminary and not robust. Resistant starch is a type of dietary fiber that resists digestion in the small intestine and is fermented by gut bacteria in the colon. This fermentation produces short-chain fatty acids (SCFAs), particularly butyrate, which has anti-inflammatory properties and is known to support colonic health. Several small clinical and preclinical studies have investigated the effect of RS supplementation in patients with Crohn's Disease or in animal models of inflammatory bowel disease (IBD).

Some studies have reported that resistant starch can increase the production of butyrate, improve gut barrier function, and modulate the composition of gut microbiota in ways that may be beneficial for people with Crohn's Disease. For example, a small randomized controlled trial (Benjamin et al., 2011) showed that RS supplementation increased fecal butyrate concentrations in patients with quiescent Crohn's Disease, but did not significantly affect clinical outcomes. Animal studies have also demonstrated that RS may reduce colonic inflammation. However, large-scale, high-quality clinical trials are lacking, and current clinical guidelines do not recommend resistant starch as a standard therapy for Crohn's Disease.

In summary, while there is a scientific rationale and some early research supporting the use of resistant starch to modulate gut inflammation and microbiota in Crohn's Disease, the supporting evidence is limited and more research is needed to establish its effectiveness.

More about Resistant Starch
More about Crohn's Disease

Products containing Resistant Starch

We currently have no products on Vitabase that contain this ingredient.