Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glutamine is an amino acid that plays a key role in various metabolic processes, including protein synthesis and immune function. Its use for "debility"—a broad term describing general weakness or lack of energy—has some scientific basis, though the strength of evidence is limited and primarily applies to specific subgroups.

Research has shown that L-glutamine supplementation can benefit individuals experiencing muscle wasting, critical illness, or recovery from major surgery, all of which can manifest as debility. For instance, some studies in cancer patients undergoing chemotherapy, HIV/AIDS patients, and those with severe burns or trauma have demonstrated improvements in muscle mass, immune function, and overall recovery with glutamine supplementation. In these cases, glutamine may help counteract the catabolic state that leads to weakness and fatigue.

However, evidence for L-glutamine’s effectiveness in addressing non-specific, general debility in otherwise healthy individuals is sparse. Most clinical trials focus on populations with defined medical conditions that result in debility. The theoretical rationale stems from glutamine’s role as a fuel for rapidly dividing cells (such as those in the immune and gastrointestinal systems) and its importance in nitrogen transport. Despite these mechanisms, high-quality, large-scale studies supporting its use for general debility are lacking. Thus, while there is some scientific validation for its use in specific types of medically-related debility, its general use for all-purpose weakness is not strongly supported by current evidence.

More about l-glutamine
More about Debility

Other ingredients used for Debility

Other health conditions supported by l-glutamine

Products containing l-glutamine

Douglas Laboratories 5-HTP Plus Formula
Designs For Health Amino-D-Tox™
Designs For Health Amino-D-Tox™
Pure Encapsulations Amino-NR
Pure Encapsulations Amino Replete
Designs For Health BCAA Powder with L-Glutamine
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Thorne EnteroMend NSF
Pure Encapsulations EpiIntegrity
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Integrity
Pure Encapsulations G.I. Integrity
Designs For Health GI Revive®
Designs For Health GI Revive®
Metagenics GI Sustain™ Powder
Metagenics Glutagenics® powder
Integrative Therapeutics Glutamine Forte Drink Mix
Vitabase HGH Complex
Designs For Health IBSynergy™
Klean Athlete Klean Essential Aminos + HMB®
Klean Athlete Klean Isolate ™
Thorne L-Glutamine
Pure Encapsulations l-Glutamine
Designs For Health L-Glutamine
Douglas Laboratories L-Glutamine
Pure Encapsulations l-Glutamine 500 mg
Pure Encapsulations l-Glutamine 850 mg
Pure Encapsulations l-Glutamine 850 mg
Designs For Health L-Glutamine Powder
Designs For Health L-Glutamine Powder
Douglas Laboratories L-Glutamine Powder
Thorne L-Glutamine Powder NSF
Pure Encapsulations Liver G.I. Detox
Thorne MediClear Plus
Integrative Therapeutics Multiplex-1 No-Iron
Douglas Laboratories Muscle Protect™ with HMB®
Designs For Health Neurolink™
Integrative Therapeutics Nutrivitamin No-Iron
Pure Encapsulations PureBi•Ome™ G.I.
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C Chewable
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations UltraDetox 10-Day Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana