Evidence supporting the use of: Glucose
For the health condition: Dehydration
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Glucose is scientifically validated as a component in the treatment of dehydration, especially in cases related to diarrhea or other causes of fluid loss. The foundational evidence comes from decades of research into oral rehydration therapy (ORT). ORT uses a solution containing glucose and electrolytes (notably sodium and potassium) to efficiently rehydrate individuals, particularly children with acute diarrheal illnesses. The rationale for including glucose is based on the physiology of sodium-glucose co-transport in the small intestine. The presence of glucose enhances the absorption of sodium and, by extension, water, through the intestinal mucosa. This mechanism was elucidated in the 1960s and led to the widespread adoption of oral rehydration solutions (ORS) by global health organizations, including the World Health Organization (WHO) and UNICEF.
Numerous clinical trials and meta-analyses have established that ORS containing glucose significantly reduces mortality and morbidity from dehydration due to diarrheal diseases. The effectiveness of glucose-based ORS is considered one of the most significant medical advancements of the 20th century, saving millions of lives worldwide. The standard WHO-ORS formula includes both glucose and salts, and the addition of glucose is essential for optimal water and electrolyte absorption. Thus, the use of glucose to support and treat dehydration is strongly grounded in scientific evidence.
Other health conditions supported by glucose
Athletic and Exercise AidsBody Building
Concentration (poor)
Debility
Dehydration
Energy (lack of)
Fatigue
Hypoglycemia
Memory and Brain Function
Wasting
Weight Gain