Evidence supporting the use of: Aniracetam
For the health condition: Dementia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Aniracetam is a nootropic compound belonging to the racetam family, initially developed in the 1970s. Its use in the context of dementia, particularly Alzheimer's disease and other cognitive disorders, is supported by some scientific studies, primarily from animal research and a limited number of small human trials. These studies suggest that Aniracetam may enhance memory, learning, and cognitive function through modulation of neurotransmitters such as acetylcholine and glutamate, as well as by exerting neuroprotective and anti-anxiety effects. In several small-scale clinical trials conducted in Europe and Japan, some cognitive benefits were observed in patients with mild to moderate dementia, including improvements in memory and attention. However, these studies often suffered from methodological limitations, such as small sample sizes and short durations.

Currently, larger, high-quality randomized controlled trials are lacking, and Aniracetam is not approved by regulatory agencies like the FDA for the treatment of dementia. Its use remains off-label, and it is more commonly utilized in some European and Asian countries than in the United States. Overall, while there is preliminary scientific evidence suggesting potential cognitive benefits, the strength of this evidence is modest, and more robust research is needed to establish Aniracetam’s efficacy and safety in the management of dementia.

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Products containing Aniracetam

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