Evidence supporting the use of: Anthocyanin
For the health condition: Dementia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanins are natural pigments found in various fruits and vegetables, particularly berries, and are known for their antioxidant properties. There is some scientific interest in their potential neuroprotective effects, including for dementia. Preclinical studies (in vitro and animal models) have shown that anthocyanins may reduce oxidative stress, inflammation, and amyloid-beta aggregation—factors implicated in the pathogenesis of Alzheimer’s disease and other dementias. Several small-scale human studies and epidemiological research suggest that diets rich in anthocyanins (such as those high in berries) may be associated with slower cognitive decline in older adults. However, these studies are largely observational, with few randomized controlled trials (RCTs) directly investigating anthocyanin supplementation in dementia patients. Meta-analyses indicate modest cognitive benefits from flavonoid-rich diets, but the evidence is not strong enough to recommend anthocyanins as a treatment or definitive preventive measure for dementia. Thus, while there is a scientific rationale and some preliminary evidence, more robust clinical trials are needed to establish efficacy.

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Products containing Anthocyanin

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