Evidence supporting the use of: Beta Hydroxybutyrate
For the health condition: Dementia
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Beta Hydroxybutyrate (BHB) is a ketone body produced during states of low carbohydrate availability, such as fasting or ketogenic diets. There is growing scientific interest in BHB’s potential to support brain function, particularly in the context of neurodegenerative diseases like dementia and Alzheimer’s disease. The rationale stems from evidence that brain glucose metabolism is impaired in these conditions, while ketone metabolism remains relatively preserved. Some small clinical trials and animal studies have shown that supplementation with exogenous ketones, including BHB, can increase brain ketone levels and may lead to modest improvements in cognitive performance in patients with mild cognitive impairment or early Alzheimer’s disease. However, the number of human clinical studies is limited, sample sizes are small, and results are preliminary. Larger, well-controlled trials are needed to confirm efficacy, determine optimal dosing, and assess long-term safety. Thus, while the use of BHB in dementia is supported by plausible biological mechanisms and early clinical research, the strength of current evidence is low to moderate.
Other ingredients used for Dementia
acetyl l-carnitinealgal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
astaxanthin
bilberry
blueberry
Chinese salvia root
citicoline
turmeric
DHA (docosahexaeonic acid)
fish oil
folate
ginger
ginkgo biloba
grape
green tea
huperzine A
l-carnosine
lion's mane
luteolin
marine lipid
melatonin
omega-3 fatty acids
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
quercetin
reishi mushroom
resveratrol
selenium
Urolithin A
vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
royal jelly
Anserine
Alpha glyceryl
Acetylcholine
Aniracetam
Butylphthalide
Beta-hydroxybutyrate
Basidiomycota
Brahmi
Bacopa
bacoside
Centrophenoxine
Curcuminoid
Convolvulus prostratus
Folic Acid
Fo-Ti
Fatty acids
Flavanols
Flavones
Ketone Salts
Other health conditions supported by Beta Hydroxybutyrate
Alzheimer's DiseaseCancer (natural therapy for)
Cardiovascular Disease
Dementia
Depression
Energy (lack of)
Epilepsy
Exercise
Fat Metabolism (poor)
Fatigue
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Metabolic Syndrome
Migraine
Multiple Sclerosis
Nerve Damage
Parkinson's Disease
Seizures
Wasting
Weight Loss