Evidence supporting the use of: Blueberry
For the health condition: Dementia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Blueberries have attracted scientific interest for their potential role in supporting cognitive function and possibly delaying the progression of dementia, including Alzheimer’s disease. The primary bioactive compounds in blueberries are anthocyanins and other flavonoids, which have demonstrated antioxidant and anti-inflammatory properties in laboratory studies. These mechanisms are thought to counteract oxidative stress and neuroinflammation, both implicated in the pathogenesis of dementia. A number of animal studies have shown that diets enriched with blueberries can improve memory and reduce markers of neurodegeneration. In humans, several small-scale randomized controlled trials have suggested that blueberry supplementation may enhance certain aspects of cognitive performance, particularly in older adults with mild cognitive impairment. For example, a 2010 study published in the "Journal of Agricultural and Food Chemistry" found that daily blueberry juice consumption improved memory in older adults over 12 weeks. More recent trials, however, have produced mixed results, with some failing to find significant benefits. Currently, no large-scale clinical trials have established blueberries as an effective treatment or preventive measure for dementia, and the evidence remains preliminary. Existing data are promising but insufficient to warrant firm recommendations. While blueberries are a nutritious fruit and may contribute to overall brain health as part of a balanced diet, they should not be regarded as a standalone intervention for dementia.

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