Evidence supporting the use of: Ginseng (unspecified)
For the health condition: Dementia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginseng, particularly Panax ginseng and Panax quinquefolius, has been studied for its potential cognitive benefits, including possible roles in supporting dementia. Evidence is modest but present: several small randomized controlled trials and animal studies suggest that ginsenosides, the active components in ginseng, may offer neuroprotective effects, enhance cholinergic neurotransmission, and reduce oxidative stress—all factors relevant in dementia pathophysiology. Some clinical studies have reported improvements in cognitive function and memory in patients with Alzheimer's disease or mild cognitive impairment when supplemented with ginseng, usually as an adjunct to conventional therapy. However, these studies are typically of short duration, have small sample sizes, and sometimes lack rigorous controls. Systematic reviews and meta-analyses conclude that while ginseng shows some promise, the quality of evidence is low and results are inconsistent. Ginseng has a long history of traditional use for enhancing memory and vitality in East Asian medicine, but its application specifically for dementia is a more recent, scientifically investigated claim. Overall, ginseng cannot be considered a well-established treatment for dementia, but there is preliminary scientific validation that warrants further investigation.

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