Evidence supporting the use of: Vitamin E (not specified)
For the health condition: Dementia

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E has been studied for its potential role in supporting or treating dementia, particularly Alzheimer’s disease, due to its antioxidant properties. Some clinical trials, such as the 1997 study by Sano et al. published in the New England Journal of Medicine, suggested that high-dose vitamin E (2000 IU/day) could modestly slow the progression of Alzheimer’s disease in patients with moderate disease, delaying clinical milestones like nursing home placement. However, subsequent and larger studies have provided mixed results. For instance, the 2014 TEAM-AD VA Cooperative Randomized Trial found a small benefit in functional decline but no effect on cognitive decline. Meta-analyses and systematic reviews generally conclude that the evidence is inconsistent and not strong enough to recommend routine use of vitamin E for dementia, especially given concerns about potential risks (e.g., increased mortality with high doses). Overall, while there is some scientific investigation and limited support, the evidence is weak and not definitive. Vitamin E is not part of standard guideline-based management for dementia, and its use should be approached cautiously, considering potential risks and lack of robust benefit.

More about Vitamin E (not specified)
More about Dementia

Products containing Vitamin E (not specified)

We currently have no products on Vitabase that contain this ingredient.