Evidence supporting the use of: Bacoside
For the health condition: Depression

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacoside, the primary active constituent of Bacopa monnieri (commonly known as Brahmi), has been investigated for its potential neuropsychological effects, including support for depression. The scientific evidence supporting its use in depression specifically is limited but emerging. Preclinical studies in animal models have demonstrated that bacosides may exert antidepressant-like effects, potentially through modulation of neurotransmitter levels (such as serotonin, dopamine, and norepinephrine) and reduction of oxidative stress in the brain. Some small-scale human clinical studies and systematic reviews have suggested that Bacopa monnieri extracts may improve mood, reduce anxiety, and enhance cognitive function, though the primary focus has been on cognitive enhancement rather than direct treatment of depressive disorders.

To date, there are few high-quality, large-scale randomized controlled trials examining the direct effects of bacoside or Bacopa monnieri extracts on clinical depression. The available evidence suggests possible benefit, but it is not robust enough to warrant strong clinical recommendations. Most professional guidelines do not list bacoside as a treatment for depression, though it continues to be explored as a supportive or adjunctive therapy. In summary, while bacoside is traditionally used for cognitive and mood-related benefits in Ayurvedic medicine, the scientific evidence for its use specifically in depression is preliminary and rated as low to moderate in quality.

More about bacoside
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Other ingredients used for Depression

5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
Acetyl L-carnitine
Acetyl-L-Tyrosine
Agarwood
Agmatine
Albizia
algal oil
Algal protein
Almond fruit
Alpha lactalbumin
alpha-linolenic acid (ALA)
alpinia galangal
amino acids
Amor seco
anchovies
Angelica
aniracetam
anthocyanins
apigenin
Ardisia
arginine creatine
ashwagandha
Asteraceae
Bacopa
Bacopin
bacoside
baicalin
Baikal Skullcap
basil
bee products
Beef liver
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacterium longum
biogenic amine
biopterin
Black Hellebore
black tea
blackboard tree
brahmi
Broussonetia
Butea monosperma
butyric acid
bасора
Caesalpinia crista
caffeine
Camellia sinensis
cannabichromene
cannabidiol
Cannabis sativa oil
Canscora
caryophyllene
catalpol
Centella asiatica
chamomile
Chinese raisintree
Chinese salvia root
chocolate
choline
cistanche
citicoline
Citrus
Clary sage
clove
cocoa
coconut
Codonopsis
coenzyme Q10 (CoQ10)
cola nut
commiphora
Convolvulus pluricaulis
Convolvulus prostratus
cordyceps
cowslip
creatine
creatine monohydrate
crocin
Curcuma
curcumen
curcumin
Curcuminoid
Cymbopogon martini
D-phenylalanine
damiana
devil\'s club
DHA (docosahexaenoic acid)
DHEA
DHEA (dehydroepiandrosterone)
docosahexaenoic Acid
dodder
dopamine
DPA (docosapentaenoic acid)
egg
eicosapentaenoic acid
Eicosatetraenoic acid
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
estrogen
fatty acids
fish
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flavonoids
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fungus
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ginkgo biloba
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gotu kola
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Gypenoside
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hemp
hemp oil
hericium mushroom
Honokiol
hyperforin
Hypericin
Hypericum
icariin
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inositol
inositol phosphate
isoliquiritigenin
jasmine
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jujube
kanna
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krill oil
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L-carnosine
L-glycine
L-methionine
L-phenylalanine
L-theanine
L-tryptophan
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lactalbumin
lactium casein decapeptide
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Large-leaved linden
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lavender
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maca
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Nymphaea caerulea
Nymphaea nouchali
omega-3 fatty acids
Onosma bracteatum
Oroxylum indicum
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spirulina
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star of Bethlehem
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suma
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Yuzu
Zinc
Zingiberene
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Products containing bacoside

We currently have no products on Vitabase that contain this ingredient.