Evidence supporting the use of: Curcuma
For the health condition: Depression

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcuma, most commonly referring to Curcuma longa (turmeric), has been used traditionally in various cultures, particularly in South Asian medicine, for a range of ailments, including mood disorders. In recent years, scientific interest has grown regarding its potential antidepressant effects, largely attributed to its main active compound, curcumin. Several randomized controlled trials and meta-analyses have investigated curcumin supplementation in individuals with major depressive disorder and depressive symptoms. These studies generally report modest but statistically significant improvements in depressive symptoms compared to placebo. Proposed mechanisms include curcumin’s anti-inflammatory and antioxidant properties, as well as its potential to modulate neurotransmitters such as serotonin and dopamine. However, the quality of evidence is limited by small sample sizes, short study durations, and issues with curcumin's bioavailability. Larger and longer-term studies are needed to draw firm conclusions, but current scientific evidence does suggest that Curcuma (specifically curcumin) may have a supportive role as an adjunct in the management of depression. This evidence base is stronger than for many other herbal remedies, but not yet sufficient for strong clinical recommendations.

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Other ingredients used for Depression

5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
Acetyl L-carnitine
Acetyl-L-Tyrosine
Agarwood
Agmatine
Albizia
algal oil
Algal protein
Almond fruit
Alpha lactalbumin
alpha-linolenic acid (ALA)
alpinia galangal
amino acids
Amor seco
anchovies
Angelica
aniracetam
anthocyanins
apigenin
Ardisia
arginine creatine
ashwagandha
Asteraceae
Bacopa
Bacopin
bacoside
baicalin
Baikal Skullcap
basil
bee products
Beef liver
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacterium longum
biogenic amine
biopterin
Black Hellebore
black tea
blackboard tree
brahmi
Broussonetia
Butea monosperma
butyric acid
bасора
Caesalpinia crista
caffeine
Camellia sinensis
cannabichromene
cannabidiol
Cannabis sativa oil
Canscora
caryophyllene
catalpol
Centella asiatica
chamomile
Chinese raisintree
Chinese salvia root
chocolate
choline
cistanche
citicoline
Citrus
Clary sage
clove
cocoa
coconut
Codonopsis
coenzyme Q10 (CoQ10)
cola nut
commiphora
Convolvulus pluricaulis
Convolvulus prostratus
cordyceps
cowslip
creatine
creatine monohydrate
crocin
Curcuma
curcumen
curcumin
Curcuminoid
Cymbopogon martini
D-phenylalanine
damiana
devil\'s club
DHA (docosahexaenoic acid)
DHEA
DHEA (dehydroepiandrosterone)
docosahexaenoic Acid
dodder
dopamine
DPA (docosapentaenoic acid)
egg
eicosapentaenoic acid
Eicosatetraenoic acid
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
estrogen
fatty acids
fish
fish oil
fish protein
flavonoids
flavonols
folate
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folinic acid
fragrant rosewood
frankincense
fungus
gardenia
gastrodia
gastrodin
ginger
ginkgo biloba
ginseng
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Glutamate
Glycine
gotu kola
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green tea
Griffonia simplicifolia
guanidinoacetic acid
Gypenoside
Helicteres isora
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hemp
hemp oil
hericium mushroom
Honokiol
hyperforin
Hypericin
Hypericum
icariin
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Indian tinospora
inositol
inositol phosphate
isoliquiritigenin
jasmine
Jatamansi
jujube
kanna
Kokilaksha
krill oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-carnosine
L-glycine
L-methionine
L-phenylalanine
L-theanine
L-tryptophan
l-tyrosine
lactalbumin
lactium casein decapeptide
lactoglobulin
Large-leaved linden
Lavandin
lavender
Lebbek
lemon balm
lemongrass
ligustilides
limonene
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lion's mane
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maca
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Mulungu
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Nutmeg
Nymphaea caerulea
Nymphaea nouchali
omega-3 fatty acids
Onosma bracteatum
Oroxylum indicum
Osthole
Oxindole alkaloids
paeoniflorin
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Patchouli oil
Pentacyclic triterpenoids
peony
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phenolic compounds
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phosphatidylserine
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polygala root
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quercetin
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rose
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rosemary
rosmarinic acid
royal jelly
Rubiaceae
rue
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sage
Salidroside
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sceletium
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selenium
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Shilajit
Sichuan Lovage
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
Spikenard
spirulina
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star of Bethlehem
Stereospermum
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suma
Sweet Orange alcohol
Tea
Terpenoids
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thyroid substance
Tongkat ali
trace minerals
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turmeric
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velvet bean
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vitamin B
vitamin B12
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vitamin D3
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Withanolides
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Xanthophyll
Xylaria nigripes
Yerba buena
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Ylang ylang
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Yuzu
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Products containing Curcuma

We currently have no products on Vitabase that contain this ingredient.