Evidence supporting the use of: Marine lipid (unspecified)
For the health condition: Depression

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Marine lipids, particularly omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been studied for their potential role in supporting or treating depression. Multiple randomized controlled trials and meta-analyses suggest that supplementation with marine-derived omega-3s, especially those with higher EPA content, can have a modest beneficial effect on depressive symptoms, particularly in individuals with major depressive disorder or those not responding fully to standard antidepressant treatment. The proposed mechanisms include anti-inflammatory effects, modulation of neurotransmitter pathways, and neuroprotective actions.

However, the quality and consistency of evidence vary. Some large trials have found only minimal or no benefit, and heterogeneity in study design, dosage, and participant characteristics complicates interpretation. Systematic reviews and meta-analyses (for example, Appleton et al., 2021; Mocking et al., 2016) generally conclude that there is a small but significant effect, especially for EPA-predominant preparations. Guidelines from some psychiatric associations cautiously recommend marine lipid supplementation as an adjunctive treatment for depression, recognizing the generally favorable safety profile.

In summary, while marine lipids are not a primary or stand-alone treatment for depression, there is moderate scientific evidence supporting their adjunctive use, particularly in specific populations or when EPA content is high.

More about Marine lipid (unspecified)
More about Depression

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algal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
ashwagandha
waterhyssop
basil
bergamot
beta caryophyllene
bifidobacterium longum
black tea
Indian frankincense
bасора
caffeine
cannabis sativa oil
chamomile
Chinese salvia root
choline
citicoline
clove
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
turmeric
curcumin
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flavonols
folate
gardenia
ginger
ginkgo biloba
ginseng
gotu kola
greek mountain tea
green tea
hemp oil
Indian tinospora
inositol
jujube
krill oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
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L-glycine
L-methionine
L-phenylalanine
L-theanine
L-tryptophan
l-tyrosine
lactium casein decapeptide
lavender
lion's mane
lithium orotate
liquid liver fractions
luteolin
maca
mackerel
magnesium
magnolia
marine lipid
matcha
melatonin
moringa
muira puama
n-acetyl-cysteine (NAC)
Acetyl-L-Tyrosine
omega-3 fatty acids
phenolic compounds
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
prebiotic blend (proprietary)
pregnenolone
protein
butyric acid
quercetin
reishi mushroom
resveratrol
rhodiola
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
sceletium
selenium
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
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valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
whey protein
zinc
suma
gastrodia
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alpinia galangal
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trace minerals
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thyroid substance
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Bacopin
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Baicalin
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Monkey Flower
Crocin
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cola nut
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Devil's Club
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Egg
Eicosatetraenoic acid
Eicosapentaenoic Acid
Estrogen
Folinic Acid
Folic Acid
Flavonoids
Fragrant Rosewood
Fish
Fatty acids
Fungus
Frankincense
Guanidinoacetic acid
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Glutamate
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Gastrodin
Honokiol
Hypericin
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Hypericum
hyperforin
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isoliquiritigenin
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Indian Fagonia
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jasmine
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Methylcobalamin
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Methylxanthine
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Marine fat
Magnolol
Mulungu
Mesembrine
Nardostachys
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Products containing Marine lipid (unspecified)

We currently have no products on Vitabase that contain this ingredient.