Evidence supporting the use of: Marine oil (unspecified)
For the health condition: Depression

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Marine oil, typically referring to fish oil rich in omega-3 polyunsaturated fatty acids (notably EPA and DHA), has a moderate level of scientific evidence supporting its use in the management of depression. Multiple randomized controlled trials and meta-analyses have examined the efficacy of omega-3 supplementation for depressive symptoms. The majority of evidence suggests that EPA-predominant formulations may have a small but significant benefit for people with major depressive disorder, particularly as an adjunct to standard antidepressant treatments. The proposed mechanisms include anti-inflammatory effects, modulation of neurotransmitter pathways, and alterations in cell membrane fluidity. However, results across studies are mixed, with some trials showing no significant effect compared to placebo, especially in populations without clinical depression or when DHA-predominant oils are used.

Clinical guidelines from some psychiatric and medical organizations suggest a possible adjunctive role for omega-3s (especially when EPA content is higher than DHA), but they are not recommended as a first-line standalone treatment. Marine oil is not traditionally used for depression; its application is based on recent scientific research. In summary, while the evidence is not unequivocal, there is moderate scientific validation for the use of marine oil (specifically high-EPA fish oil) as an adjunct in treating depression.

More about Marine oil (unspecified)
More about Depression

Other ingredients used for Depression

5-Hydroxytryptophan (5-HTP)
Acetyl L-carnitine
algal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
ashwagandha
waterhyssop
basil
bergamot
beta caryophyllene
bifidobacterium longum
black tea
Indian frankincense
bасора
caffeine
cannabis sativa oil
chamomile
Chinese salvia root
choline
citicoline
clove
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
turmeric
curcumin
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flavonols
folate
gardenia
ginger
ginkgo biloba
ginseng
gotu kola
greek mountain tea
green tea
hemp oil
Indian tinospora
inositol
jujube
krill oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-carnosine
L-glycine
L-methionine
L-phenylalanine
L-theanine
L-tryptophan
l-tyrosine
lactium casein decapeptide
lavender
lion's mane
lithium orotate
liquid liver fractions
luteolin
maca
mackerel
magnesium
magnolia
marine lipid
matcha
melatonin
moringa
muira puama
n-acetyl-cysteine (NAC)
Acetyl-L-Tyrosine
omega-3 fatty acids
phenolic compounds
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
prebiotic blend (proprietary)
pregnenolone
protein
butyric acid
quercetin
reishi mushroom
resveratrol
rhodiola
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
sceletium
selenium
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
spirulina
tongkat ali
Almond fruit
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
whey protein
zinc
suma
gastrodia
mugwort
alpinia galangal
commiphora
blackboard tree
caesalpinia crista
peony
lingzhi
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kanna
cistanche
dodder
morinda
royal jelly
polyphenols
trace minerals
St. John's Wort
yerba mate
hypothalamus
cocoa
thyroid substance
star of Bethlehem
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
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Baicalin
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Caryophyllene
Monkey Flower
Crocin
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Catalpol
Codonopsis
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Chinese Raisintree
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Cymbopogon Martini
Centella asiatica
Chocolate
Creatine
Curcuma
Cowslip
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cola nut
Canscora
Cannabichromene
Docosahexaenoic Acid
D-phenylalanine
DHEA
Devil's Club
Dopamine
Egg
Eicosatetraenoic acid
Eicosapentaenoic Acid
Estrogen
Folinic Acid
Folic Acid
Flavonoids
Fragrant Rosewood
Fish
Fatty acids
Fungus
Frankincense
Guanidinoacetic acid
Ginsenosides
Griffonia simplicifolia
Gypenoside
Growth factors
Glutamate
Glycine
Gastrodin
Honokiol
Hypericin
Hellebore
Hypericum
hyperforin
Helicteres isora
Hericium mushroom
Hemp
isoliquiritigenin
Long Pepper
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Indian Fagonia
Inositol phosphate
jasmine
Jatamansi
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lemon balm
Lebbek
Ligustilides
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Lavandin
Lycopodium
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Little ironweed
Lactalbumin
Lactoglobulin
Linalool
Lipids
Methylcobalamin
Marine Protein
Milk Protein
Methylxanthine
Mimosa
Meadow sage
Marine fat
Magnolol
Mulungu
Mesembrine
Nardostachys
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Oroxylum indicum
Onosma bracteatum
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Pulsatilla
Patchouli oil
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Polyunsaturated Fat
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Rosabin
Rosmarinic Acid
Rubiaceae
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Schizochytrium Oil
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Sensitive Plant
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Shellfish
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Stereospermum
Shilajit
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Sarcosine
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Terpenoids
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Uncaria
Uridine
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Withanolides
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Products containing Marine oil (unspecified)

We currently have no products on Vitabase that contain this ingredient.