Evidence supporting the use of: Sichuan Lovage
For the health condition: Depression

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sichuan Lovage (Ligusticum chuanxiong), known as Chuanxiong in traditional Chinese medicine (TCM), has a long history of use primarily for promoting blood circulation, alleviating pain, and treating headaches and gynecological disorders. Its use for depression is primarily rooted in traditional practice rather than robust scientific validation. In TCM, depression is sometimes conceptualized as a disturbance of the movement of “Qi” and blood, and formulas containing Chuanxiong are used to “invigorate blood” and “dispel wind,” which are believed to help with mood disorders.

There is very limited scientific evidence directly supporting the efficacy of Sichuan Lovage for depression. Some animal studies and in vitro experiments suggest that compounds in Chuanxiong, such as ligustilide and ferulic acid, may have neuroprotective or anti-inflammatory effects, which might be theoretically relevant for mood regulation. However, clinical trials in humans specifically examining its antidepressant effects are scarce or of low quality. Most modern research is preliminary and focuses on Chuanxiong’s vascular and neurological effects rather than direct treatment of depressive disorders.

In summary, the use of Sichuan Lovage for depression is justified primarily by traditional use in Chinese medicine, with little high-quality scientific evidence to support its efficacy for this condition.

More about Sichuan Lovage
More about Depression

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alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
ashwagandha
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basil
bergamot
beta caryophyllene
Bifidobacterium longum
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caffeine
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chamomile
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choline
citicoline
clove
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
turmeric
curcumin
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flavonols
folate
gardenia
ginger
ginkgo biloba
ginseng
gotu kola
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green tea
hemp oil
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inositol
jujube
krill oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
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L-glycine
L-methionine
L-phenylalanine
L-theanine
L-tryptophan
l-tyrosine
lactium casein decapeptide
lavender
lion's mane
lithium orotate
liquid liver fractions
luteolin
maca
magnesium
magnolia
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Melatonin
Moringa
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N-acetyl-cysteine (NAC)
Acetyl-L-Tyrosine
omega-3 fatty acids
phenolic compounds
phosphatidylserine
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phytocannabinoids
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pomegranate
prebiotic blend (proprietary)
pregnenolone
protein
butyric acid
quercetin
reishi mushroom
resveratrol
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rosemary
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vitamin D
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creatine
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cola nut
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docosahexaenoic Acid
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DHEA
devil\'s club
dopamine
egg
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eicosapentaenoic acid
estrogen
folinic acid
folic acid
flavonoids
fragrant rosewood
fish
fatty acids
fungus
frankincense
guanidinoacetic acid
Ginsenosides
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Gypenoside
Glutamate
Glycine
gastrodin
Honokiol
Hypericin
Hellebore
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hyperforin
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hericium mushroom
hemp
isoliquiritigenin
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magnolol
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Products containing Sichuan Lovage

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