Evidence supporting the use of: Whey protin
For the health condition: Depression

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Whey protein has some scientific rationale for its potential use in supporting mood and depression, but the evidence is limited and preliminary. Whey protein is a rich source of the amino acid tryptophan, which serves as a precursor for serotonin, a neurotransmitter involved in mood regulation. Some small clinical studies and reviews have suggested that increased intake of tryptophan or tryptophan-rich proteins like whey may enhance brain serotonin levels and potentially improve mood or reduce depressive symptoms. For example, a few randomized controlled trials have indicated that whey protein supplementation could lead to improvements in stress and mild depressive symptoms, possibly by increasing brain serotonin synthesis.

However, the overall quality and quantity of evidence are low. Most studies have small sample sizes, short durations, and may not be directly applicable to clinically diagnosed depression. There is not yet strong evidence to support the use of whey protein as a primary or adjunctive treatment for depression. Major clinical guidelines for depression do not mention whey protein as a recommended intervention. Therefore, while there is some scientific interest and plausible mechanisms, the evidence currently rates as weak (2/5) and more robust research is needed before whey protein can be confidently recommended for depression support.

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Other ingredients used for Depression

5-Hydroxytryptophan (5-HTP)
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algal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
ashwagandha
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basil
bergamot
beta caryophyllene
Bifidobacterium longum
black tea
Indian frankincense
bасора
caffeine
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chamomile
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choline
citicoline
clove
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
turmeric
curcumin
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flavonols
folate
gardenia
ginger
ginkgo biloba
ginseng
gotu kola
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green tea
hemp oil
Indian tinospora
inositol
jujube
krill oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
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L-glycine
L-methionine
L-phenylalanine
L-theanine
L-tryptophan
l-tyrosine
lactium casein decapeptide
lavender
lion's mane
lithium orotate
liquid liver fractions
luteolin
maca
magnesium
magnolia
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Matcha
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Moringa
Muira puama
N-acetyl-cysteine (NAC)
Acetyl-L-Tyrosine
omega-3 fatty acids
phenolic compounds
phosphatidylserine
phospholipids
phytocannabinoids
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pomegranate
prebiotic blend (proprietary)
pregnenolone
protein
butyric acid
quercetin
reishi mushroom
resveratrol
Rhodiola
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rosemary
saffron
sage
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sceletium
selenium
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vitamin B
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vitamin B6
vitamin C
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suma
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thyroid substance
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Products containing Whey protin

We currently have no products on Vitabase that contain this ingredient.