Evidence supporting the use of: Centella asiatica
For the health condition: Dermatitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Centella asiatica (commonly known as gotu kola) has a long history of use in traditional medicine for various skin conditions, including dermatitis. More recently, scientific studies have investigated its efficacy in supporting skin barrier function, wound healing, and reducing inflammation—mechanisms relevant to dermatitis. Several in vitro and animal studies indicate that Centella asiatica extracts, particularly components such as asiaticoside and madecassoside, promote collagen synthesis, enhance antioxidant activity, and reduce pro-inflammatory cytokines, all of which may help in managing dermatitis. Small-scale clinical studies and randomized controlled trials have shown topical formulations containing Centella asiatica extracts can accelerate healing in mild eczema and reduce symptoms such as erythema, scaling, and itching. However, most studies have limitations, such as small sample sizes, short durations, or use of combination products, making definitive conclusions challenging. Despite these limitations, the evidence base is growing, and some dermatologists consider Centella asiatica-containing creams as adjuvant therapy for mild-to-moderate dermatitis. Further large-scale, high-quality clinical trials are needed to confirm efficacy and safety, but current scientific evidence moderately supports its use.
Other ingredients used for Dermatitis
AllantoinAloe vera
alpha-pinene
alpha-terpineol
anamu
Ardisia
argan nut oil
Asteraceae
avens
azelaic acid
babchi
Baphicacanthus cusia
Barleria
Bassia scoparia
bee products
bee propolis
beta caryophyllene
Bidens pilosa
birch
bisabolene
bishop\'s weed
black currant
black walnut
Bombax
Boswellic Acid
burdock
Butea monosperma
Calendula
cannabidiol
cannabigerol
Cannabis sativa oil
Carthamus
carvacrol
caryophyllene
Centella asiatica
Centella triterpenes
Centipeda
chamomile
chickweed
Chinese raisintree
chlorophyllin
chrysophanics
coconut
coconut oil
colloid
commiphora
copaiba oil
Curcuma
curcumen
Curcuminoid
Dianthus
Eclipta
emu oil
Epidermal Growth Factor
ethyl linoleate
eucalyptus
Euphorbia
fang-feng
fatty acids
fibroblast growth factor
Ficus simplicissima
flavonoids
forsythia
fulvic acid
gallic acid
gallotannin
garlic bulb
geranium
ginger
Glechoma hederacea
glyceryl monolaurate
Glycyrrhetinic acid
Gnaphalium
gotu kola
green tea
heal-all
hemp
hemp oil
henna
Himalaya berry
hyaluronic acid
Hydrocolloid
Indian fagonia
iridoid glycosides
jojoba oil
Kokilaksha
Labdanum
Lactoperoxidase
Laggera pterodonta
Lantana camara
lauric acid
Leptospermum scoparium
lichen
linseed oil
Litsea
Macaranga indica
Mahonia
mallow
Malva sylvestris
mangostin
marigold
Marine colloids
Marking Nut Tree
melaleuca alternifolia
Melia
Menthol oil
Milkweed
Mugwort
Neem tree
Niacinamide (vitamin B3)
Nigella seed
oregon grape
oriental arborvitae
Oxystelma
Palmitoylethanolamide (PEA)
Pansit-pansitan
Panthenol
Paris polyphylla
Patrinia
Pentacyclic triterpenoids
Peptides
phenolic compounds
Phyllanthus
plantain
polyphenols
pomegranate
Propolis
purified silver
quercetin
resveratrol
riboflavin (vitamin B2)
rosemary
rosmarinic acid
rue
Salvia
Sandalwood
schizonepeta
scrophularia root
Self-Heal
Sensitive Plant
Sesbania
Shark Liver Oil
Sichuan Lovage
Sicklepod
siler root
Silk protein
Solanaceae
Sophora
Southern Tsangshu
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
Squalene
Storax
Sweet Annie
Tea Tree Oil
Terpenoids
Terpinen-4-ol
Thymol
Thymoquinone
Thymus
turmeric
Violet
vitamin A
vitamin D
vitamin E
Witch Hazel
Wrightia tinctoria
xanthium (cockleburs)
Zinc
Zingiberene
Other health conditions supported by Centella asiatica
AbrasionsAnxiety
Anxiety Disorders
Arthritis
Backache
Bell's Palsy
Bleeding (internal)
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Capillary Weakness
Circulation (poor)
Convalescence
Cuts
Depression
Dermatitis
Diabetes
Edema
Fatigue
Gastritis
Gingivitis
Inflammation
Insomnia
Liver Detoxification
Memory and Brain Function
Pain (general remedies for)
Psoriasis
Scars / Scar Tissue
Stress
Ulcers
Wounds and Sores
