Evidence supporting the use of: Epidermal Growth Factor
For the health condition: Dermatitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Epidermal Growth Factor (EGF) has some scientific validation for its use in supporting or treating dermatitis, particularly in the context of atopic dermatitis and wound healing. EGF is a polypeptide that stimulates cell growth, proliferation, and differentiation by binding to its receptor, EGFR, on the cell surface. Several studies and clinical trials have investigated topical application of EGF in patients with various skin conditions, including dermatitis. For example, randomized controlled trials have demonstrated that topical EGF can accelerate healing of skin lesions, improve barrier function, and reduce inflammation in models of atopic dermatitis and other skin injuries. A 2018 study published in the "Annals of Dermatology" found that EGF ointment aided the repair of skin barrier function and reduced symptoms in patients with atopic dermatitis. Another 2015 study reported improved wound healing and reduced inflammatory markers in animal models treated with EGF.

However, while these results are promising, the body of evidence is not yet extensive or universally conclusive, and EGF is not a standard first-line therapy for dermatitis. Most studies have small sample sizes or are preclinical, and long-term safety data are limited. Nevertheless, the mechanism of action and available research provide a scientific rationale for its use as an adjunctive therapy in certain cases of dermatitis, especially where wound healing is impaired. More large-scale, high-quality clinical trials are needed to fully establish EGF’s efficacy and safety profile for routine treatment of dermatitis.

More about Epidermal Growth Factor
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alpha-pinene
beeswax
beta caryophyllene
bisabolol
black currant
black walnut
burdock
cannabis sativa oil
chamomile
coating
turmeric
forsythia
garlic bulb
ginger
gotu kola
green tea
hemp oil
hyaluronic acid
lactoperoxidase
lauric acid
niacinamide (Vitamin B3)
oregon grape
phenolic compounds
plantain
pomegranate
purified silver
quercetin
resveratrol
riboflavin (vitamin B2)
rosemary
schizonepeta
scrophularia root
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
vitamin A
vitamin D
vitamin E
zinc
chickweed
xanthium (cockleburs)
mugwort
neem tree
commiphora
siler root
oriental arborvitae
birch
polyphenols
fulvic acid
eucalyptus
menthol oil
melaleuca alternifolia
geranium
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Azelaic acid
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Asteracea
Argan nut oil
Bee Propolis
Babchi
Baphicacanthus cusia
Bidens pilosa
Bishop's Weed
Boswellic Acid
Butea monosperma
Barleria
Bisabolene
Bee products
Bombax
Bassia scoparia
Coconut
Centella triterpenes
Caryophyllene
Calendula
Chlorophyllin
coconut oil
Colloid
Carvacrol
Curcuminoid
Chinese Raisintree
Curcumen
Centella asiatica
Centipeda
Curcuma
Cannabidiol
Carthamus
Copaiba Oil
Cannabigerol
Chrysophanics
Dianthus
Epidermal Growth Factor
Eclipta
Emu Oil
Euphorbia
Ethyl Linoleate
Flavonoids
Fang-Feng
Fatty acids
Ficus simplicissima
fibroblast growth factor
Gallic Acid
Gnaphalium
Glyceryl monolaurate
Growth factors
Glechoma hederacea
Gallotannin
Glycyrrhetinic Acid
Heal-All
Hydrocolloid
Henna
Himalaya Berry
Hemp
Iridoid glycosides
Indian Fagonia
Jojoba Oil
Kokilaksha
Litsea
Lichen
Laggera pterodonta
Linseed Oil
Lantana camara
Leptospermum scoparium
Labdanum
Mallow
Melia
Malva sylvestris
Mangostin
Mahonia
Milkweed
Marine colloids
Marigold
Marking Nut Tree
Macaranga indica
Nigella Seed
Oxystelma
Propolis
Phyllanthus
Pentacyclic triterpenoids
Paris polyphylla
Pansit-pansitan
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Patrinia
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Rue
Rosmarinic Acid
Reed Herb
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Sophora
Sesbania
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Self-Heal
Sweet Annie
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Southern Tsangshu
Silk protein
Sandalwood
Sulfur
Storax
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Thymoquinone
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Products containing Epidermal Growth Factor

We currently have no products on Vitabase that contain this ingredient.