Evidence supporting the use of: Fatty acids
For the health condition: Dermatitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fatty acids, particularly essential fatty acids such as omega-3 and omega-6, are supported by scientific evidence in the management of certain forms of dermatitis, especially atopic dermatitis. These fatty acids are integral components of the skin barrier, and deficiencies in linoleic acid (an omega-6 fatty acid) have been associated with impaired skin barrier function and increased transepidermal water loss, both of which are characteristic features of atopic dermatitis. Several clinical studies and reviews have examined the effects of oral supplementation and topical application of fatty acids on dermatitis symptoms. For example, randomized controlled trials have shown that supplementation with omega-3 fatty acids (such as those found in fish oil) or omega-6 fatty acids (such as evening primrose oil or borage oil) can result in modest improvements in skin hydration, itching, and overall disease severity in some individuals with atopic dermatitis.

However, the strength of the evidence is mixed. Some systematic reviews and meta-analyses have concluded that while there is a biological rationale and some positive findings, the overall effect size is small and not consistently significant across studies. In particular, topical application of fatty acids may help restore skin barrier function, but oral supplementation shows variable results depending on the patient population and the specific type of fatty acid used. As such, while there is scientific validation for the use of fatty acids in supporting dermatitis, especially atopic dermatitis, the magnitude of benefit is moderate and not universally observed.

More about fatty acids
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Other ingredients used for Dermatitis

Aloe vera
alpha-pinene
beeswax
beta caryophyllene
bisabolol
black currant
black walnut
burdock
Cannabis sativa oil
chamomile
coating
turmeric
forsythia
garlic bulb
ginger
gotu kola
green tea
hemp oil
hyaluronic acid
Lactoperoxidase
lauric acid
Niacinamide (vitamin B3)
oregon grape
phenolic compounds
plantain
pomegranate
purified silver
quercetin
resveratrol
riboflavin (vitamin B2)
rosemary
schizonepeta
scrophularia root
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
vitamin A
vitamin D
vitamin E
Zinc
chickweed
xanthium (cockleburs)
Mugwort
Neem tree
commiphora
siler root
oriental arborvitae
birch
polyphenols
fulvic acid
eucalyptus
Menthol oil
melaleuca alternifolia
geranium
avens
alpha-terpineol
azelaic acid
Ardisia
anamu
Allantoin
Asteraceae
argan nut oil
bee propolis
babchi
Baphicacanthus cusia
Bidens pilosa
bishop\'s weed
Boswellic Acid
Butea monosperma
Barleria
bisabolene
bee products
Bombax
Bassia scoparia
coconut
Centella triterpenes
caryophyllene
Calendula
chlorophyllin
coconut oil
colloid
carvacrol
Curcuminoid
Chinese raisintree
curcumen
Centella asiatica
Centipeda
Curcuma
cannabidiol
Carthamus
copaiba oil
cannabigerol
chrysophanics
Dianthus
Epidermal Growth Factor
Eclipta
emu oil
Euphorbia
ethyl linoleate
flavonoids
fang-feng
fatty acids
Ficus simplicissima
fibroblast growth factor
gallic acid
Gnaphalium
glyceryl monolaurate
Growth factors
Glechoma hederacea
gallotannin
Glycyrrhetinic acid
heal-all
Hydrocolloid
henna
Himalaya berry
hemp
iridoid glycosides
Indian fagonia
jojoba oil
Kokilaksha
Litsea
lichen
Laggera pterodonta
linseed oil
Lantana camara
Leptospermum scoparium
Labdanum
mallow
Melia
Malva sylvestris
mangostin
Mahonia
Milkweed
Marine colloids
marigold
Marking Nut Tree
Macaranga indica
Nigella seed
Oxystelma
Propolis
Phyllanthus
Pentacyclic triterpenoids
Paris polyphylla
Pansit-pansitan
Panthenol
Patrinia
Palmitoylethanolamide (PEA)
Peptides
rue
rosmarinic acid
reed herb
Squalene
Sichuan Lovage
Sicklepod
Sophora
Sesbania
Solanaceae
Shark Liver Oil
Self-Heal
Sweet Annie
Salvia
Sensitive Plant
Southern Tsangshu
Silk protein
Sandalwood
Sulfur
Storax
Terpenoids
Thymoquinone
Terpinen-4-ol
Thymus
Thymol
Tea Tree Oil
Violet
Wrightia tinctoria
Witch Hazel
Zingiberene

Products containing fatty acids

We currently have no products on Vitabase that contain this ingredient.