Evidence supporting the use of: Lactobacillus (mixed)
For the health condition: Diverticulitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus (mixed strains) is sometimes recommended as a probiotic intervention for diverticulitis, particularly during the recovery phase after acute inflammation. The rationale is based on the modulation of gut microbiota, immune regulation, and reduction of inflammation. Scientific studies, including some randomized controlled trials and reviews, have explored the effects of probiotics (often containing Lactobacillus species) in diverticular disease broadly, which includes both diverticulosis and diverticulitis. Some evidence suggests that probiotics may help reduce symptoms such as bloating, abdominal pain, and irregular bowel habits in patients with diverticular disease. However, the quality of evidence is low to moderate, with small sample sizes and varying probiotic formulations. For acute diverticulitis specifically, evidence is limited and inconclusive. While small trials and observational studies indicate that probiotics could help restore gut flora after antibiotic therapy and potentially reduce recurrence, no large, high-quality studies have demonstrated a clear benefit for treating acute diverticulitis itself. The American Gastroenterological Association and similar bodies currently do not formally recommend probiotics for diverticulitis due to insufficient evidence. Overall, while there is some scientific rationale and preliminary data, robust, consistent clinical validation is lacking, justifying a low evidence score.

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