Evidence supporting the use of: Lactobacillus mixed)
For the health condition: Diverticulitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus (mixed species) probiotics are used as adjunctive therapy in the management of diverticulitis primarily based on scientific rationale rather than long-standing tradition. The proposed mechanism is that probiotics like Lactobacillus can help restore or maintain healthy gut microbiota, modulate inflammation, and strengthen the intestinal barrier, potentially reducing the risk of complications or recurrences associated with diverticulitis. However, the scientific evidence supporting their effectiveness specifically for diverticulitis is limited and not robust. Some small clinical trials and observational studies have investigated the use of probiotics (including Lactobacillus species) in patients with diverticular disease (which includes both diverticulitis and diverticulosis). These studies suggest a possible benefit in reducing symptoms such as abdominal pain and bloating, and in improving quality of life, but they are often limited by small sample sizes, short follow-up periods, and inconsistent methodologies. A few meta-analyses and systematic reviews have noted a lack of high-quality randomized controlled trials specifically addressing acute diverticulitis, and the results are often inconclusive or show only modest benefit. Current clinical guidelines do not universally endorse probiotics as a standard treatment for diverticulitis, though they may be considered in select cases. Overall, while there is a scientific rationale and preliminary evidence for the use of Lactobacillus, definitive, high-quality evidence is lacking, and more research is needed to establish clear recommendations.

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