Evidence supporting the use of: Lactobacillus (various species)
For the health condition: Diverticulitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus species are probiotic bacteria commonly used in clinical practice and research to support gastrointestinal health. The rationale for their use in diverticulitis, especially during remission or to prevent recurrence, is primarily based on the hypothesis that gut microbiota imbalances contribute to the pathogenesis of diverticular disease and its complications. Some studies, including small randomized controlled trials and observational studies, have explored the efficacy of probiotics (often including Lactobacillus species) in reducing symptoms or recurrence of diverticulitis. The evidence, however, is limited and heterogeneous. While a few studies suggest a potential reduction in symptoms such as abdominal pain and bloating, and a possible decrease in recurrence rates, systematic reviews and meta-analyses highlight the low quality and inconsistency of the available data. Guidelines from leading gastroenterological associations generally do not recommend probiotics as a primary treatment for acute diverticulitis but acknowledge their possible adjunct role in chronic symptomatic diverticular disease, particularly for symptom management. Overall, the scientific evidence supporting Lactobacillus for diverticulitis remains modest (rated 2/5), with the need for larger, well-designed clinical trials to draw definitive conclusions.

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