Evidence supporting the use of: 3,5-Dihydroxyphenyl acetate
For the body system: Dopamine

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

3,5-Dihydroxyphenyl acetate, also known as homoprotocatechuic acid, is a metabolite of dopamine and related catechol compounds. It is chemically related to L-DOPA (levodopa), a well-established precursor in dopamine biosynthesis. The use of 3,5-dihydroxyphenyl acetate to support the dopamine system is grounded in its role as part of the metabolic pathway associated with dopamine formation and degradation. Several scientific studies have investigated the metabolism of catecholamines and identified 3,5-dihydroxyphenyl acetate as a byproduct of dopamine breakdown, particularly in the central nervous system and peripheral tissues.

While this compound itself is not a direct precursor to dopamine (unlike L-DOPA), its close association with dopamine metabolism has led to its investigation in neurochemical studies. Research has shown that manipulating related metabolic pathways can influence dopamine levels and function, and derivatives structurally similar to 3,5-dihydroxyphenyl acetate have demonstrated neuroprotective and antioxidant properties, which may indirectly benefit the dopaminergic system. However, direct supplementation with 3,5-dihydroxyphenyl acetate is less common compared to L-DOPA or other catecholamine precursors. The scientific evidence primarily supports its relevance to dopamine biochemistry rather than as a standalone supplement to boost dopamine levels, but its presence in dopamine pathways provides a rationale for its experimental use in supporting the dopamine system. Overall, its support is scientifically grounded, though further research into its direct effects is warranted.

More about 3,5-Dihydroxyphenyl acetate
More about Dopamine

Other body systems supported by 3,5-Dihydroxyphenyl acetate

Dopamine

Products containing 3,5-Dihydroxyphenyl acetate

We currently have no products on Vitabase that contain this ingredient.