Evidence supporting the use of: Rhodiola
For the body system: Dopamine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rhodiola rosea is an adaptogenic herb traditionally used in Russia and Scandinavia for enhancing physical and mental performance. Recent scientific studies have investigated its effects on neurotransmitters, including dopamine. Some preclinical research indicates that compounds in rhodiola, such as salidroside and rosavin, may influence monoamine levels in the brain by inhibiting enzymes that degrade dopamine (e.g., monoamine oxidase) and modulating the sensitivity of dopamine receptors. These effects have been observed in animal models, where rhodiola extracts appear to increase dopamine levels in certain brain regions involved in mood and motivation. Human studies are fewer and generally focus on stress, fatigue, and mild depression, with some trials noting improvements in well-being and cognitive function that could, hypothetically, be linked to dopaminergic pathways. However, direct evidence in humans showing that rhodiola specifically supports or modulates the dopamine system is limited and indirect. Most clinical research has not measured dopamine levels or receptor activity directly. While there is some scientific rationale and preliminary evidence, the overall quality and quantity of human research are low, and the specific relationship to the "Dopamine body system" remains to be clearly established.

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