Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Trichilia catigua, commonly known as catuaba, is traditionally used in Brazilian herbal medicine. Its primary historical applications are as an aphrodisiac, a stimulant, and a remedy for fatigue and nervous conditions. The plant is reputed by local herbalists to enhance mood, energy, and libido, which has led to speculation that it may influence the dopaminergic system. However, the connection between Trichilia catigua and direct support of the dopamine body system is largely based on traditional use rather than robust scientific evidence. A few preclinical studies (primarily in rodents) have shown that some extracts of catuaba may have antidepressant-like effects, possibly involving dopaminergic pathways, but these effects have not been conclusively linked to dopamine in humans, nor have they been validated in large, rigorous clinical trials. There is a lack of direct scientific studies examining the efficacy of Trichilia catigua in modulating dopamine levels or treating dopamine-related disorders in humans. Therefore, the use of this plant to support the dopamine system is justified primarily by tradition, with limited preclinical data providing only weak support. More research is needed to substantiate its effects on dopamine or related neurological functions.

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