Evidence supporting the use of: Vitamin B6 (pyridoxamine HCl)
For the body system: Dopamine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B6, particularly in its active forms such as pyridoxamine HCl, plays a scientifically validated role in supporting the dopamine system. Vitamin B6 is a crucial cofactor for aromatic L-amino acid decarboxylase, the enzyme responsible for converting L-DOPA to dopamine in the brain. Several studies have demonstrated that inadequate B6 levels can impair dopamine synthesis, which in turn affects neurological function and mood regulation. Clinical research has shown that supplementation with vitamin B6 may assist in optimizing dopamine production, especially in populations with marginal B6 status, older adults, or individuals with increased metabolic needs.

Deficiency in vitamin B6 has been associated with neurological symptoms, some of which are linked to reduced dopaminergic function. Moreover, the importance of B6 in neurotransmitter metabolism is well-documented in biochemistry and neurology textbooks. While direct clinical trials assessing B6 supplementation for dopamine-related disorders (such as Parkinson's disease) are limited and results are mixed, the underlying biochemical rationale for ensuring adequate B6 intake to support dopamine synthesis is robust. Thus, the use of vitamin B6 for supporting the dopamine system is grounded in scientific understanding of human physiology and enzyme biochemistry.

More about Vitamin B6 (pyridoxamine HCl)
More about Dopamine

Other body systems supported by Vitamin B6 (pyridoxamine HCl)

Blood
Brain
Dopamine
Heart
Immune System
Nerves
Serotonin
Specific Neurotransmitters

Products containing Vitamin B6 (pyridoxamine HCl)

We currently have no products on Vitabase that contain this ingredient.