Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Bismuth citrate is a salt of bismuth that has been employed in gastrointestinal medicine, particularly as part of combination therapies for peptic ulcers, including duodenal ulcers. The scientific rationale for its use is well established. Bismuth compounds, including bismuth citrate and colloidal bismuth subcitrate, exhibit direct antimicrobial activity against Helicobacter pylori, the bacterium strongly linked to the development and persistence of duodenal ulcers. Multiple clinical trials and meta-analyses have demonstrated that regimens containing bismuth (often with antibiotics and a proton pump inhibitor, known as "bismuth quadruple therapy") are effective for both eradicating H. pylori and promoting ulcer healing.

Bismuth acts by suppressing H. pylori, protecting the gastric and duodenal mucosa, and possibly stimulating mucosal defense mechanisms. It also has a minor direct antacid effect and can bind toxins. Its effectiveness in ulcer healing has been shown to be similar to that of H2-receptor antagonists in some studies, particularly prior to the widespread use of proton pump inhibitors. The use of bismuth citrate is supported in international guidelines for the treatment of H. pylori-associated ulcers, especially in areas with high antibiotic resistance or prior treatment failures. Side effects are generally mild and reversible. Thus, the use of bismuth citrate in supporting or treating duodenal ulcers is underpinned by solid scientific evidence, particularly in the context of H. pylori infection.

More about Bismuth Citrate
More about Duodenal Ulcers

Other ingredients used for Duodenal Ulcers

aloe vera
cabbage leaf
turmeric
forsythia
marshmallow
mastic gum
slippery elm bark
zinc

Other health conditions supported by Bismuth Citrate

Acid Indigestion
Duodenal Ulcers
Gastritis
Infection
Infection (bacterial)
Ulcers

Products containing Bismuth Citrate

We currently have no products on Vitabase that contain this ingredient.