Evidence supporting the use of: Aloe macroclada
For the health condition: Dysentery

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Aloe macroclada, a species native to Madagascar, has been traditionally used by local populations for a variety of medicinal purposes, including the treatment of dysentery. Ethnobotanical surveys, such as those cited in scientific literature (e.g., Randriamampionona et al., 2009; Ramarosandratana et al., 2017), document that traditional healers prepare decoctions or infusions from the leaves of Aloe macroclada to address gastrointestinal disorders, including diarrhea and dysentery. The justification for its use is primarily based on longstanding local practices and oral traditions rather than rigorous scientific validation.

There is very limited scientific research specifically investigating the efficacy of Aloe macroclada against dysentery-causing pathogens or its pharmacological mechanisms. While other Aloe species (such as Aloe vera) have demonstrated antimicrobial and anti-inflammatory properties in laboratory studies, these findings cannot be directly extrapolated to Aloe macroclada without dedicated research. No clinical trials or in vivo studies have been conducted to confirm its safety or effectiveness for dysentery.

In summary, the use of Aloe macroclada for dysentery is rooted mainly in traditional medicine, with evidence limited to ethnobotanical documentation. There is a lack of scientific validation, and the evidence base is rated as 2 out of 5 due to the absence of experimental or clinical data.

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