Evidence supporting the use of: Ligusticum (Unspecified)
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ligusticum species, particularly Ligusticum chuanxiong (commonly known as Chuanxiong or Szechuan lovage), are widely used in Traditional Chinese Medicine (TCM) for the treatment of dysmenorrhea (painful menstruation). Historical texts and pharmacopeias document its use to "invigorate blood" and "dispel wind," addressing symptoms such as menstrual cramps and irregular menstruation. Chuanxiong is a common ingredient in well-established TCM formulas for women's reproductive health, such as Shaofu Zhuyu Tang and Siwu Tang, both of which are prescribed for dysmenorrhea.

Scientific studies on Ligusticum's efficacy for dysmenorrhea are limited. Some preclinical research suggests that its active compounds, such as ligustilide and ferulic acid, may exhibit anti-inflammatory, analgesic, and antispasmodic properties, which could theoretically alleviate menstrual pain. However, clinical trials in humans remain sparse and often methodologically weak, making it difficult to draw firm conclusions about its effectiveness. Systematic reviews note the lack of high-quality randomized controlled trials to confirm its benefits for dysmenorrhea.

In summary, the use of Ligusticum for dysmenorrhea is primarily justified by a long-standing tradition in herbal and Chinese medicine. While some pharmacological rationale exists, robust scientific validation is lacking, and its evidence rating for this indication remains low.

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