Evidence supporting the use of: Squaw Vine
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Squaw Vine (Mitchella repens) has a long history of use in traditional herbal medicine, particularly among Native American tribes and 19th-century Western herbalists. It was commonly recommended as a uterine tonic, especially in the context of preparing for childbirth and supporting various female reproductive complaints, including dysmenorrhea (painful menstruation). Historical herbal texts, such as those by the Eclectic physicians, describe Squaw Vine as an ingredient in formulas intended to ease menstrual cramps and regulate menstrual cycles. However, these recommendations are rooted in anecdotal accounts and tradition rather than rigorous scientific investigation.

To date, there is a lack of robust scientific studies—such as randomized controlled trials or pharmacological research—specifically evaluating the efficacy of Squaw Vine for dysmenorrhea. The plant contains compounds such as tannins and saponins, but their direct effects on menstrual pain have not been substantiated in modern clinical literature. Consequently, while Squaw Vine continues to be found in some traditional and folk herbal formulations for menstrual issues, its use for dysmenorrhea is supported by tradition rather than validated by contemporary science.

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