Evidence supporting the use of: Vitamin B6 (pyridoxal 5-phosphate)
For the health condition: Dysmenorrhea

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin B6 (pyridoxal 5-phosphate) is traditionally used for the management of dysmenorrhea (painful menstruation), although scientific evidence supporting its efficacy is limited and not robust. The rationale for its use stems primarily from its role in neurotransmitter synthesis and potential effects on hormone regulation. Historically, some health practitioners and traditional medicine systems have recommended Vitamin B6 to alleviate premenstrual symptoms, including cramps and mood disturbances, based on the vitamin's involvement in serotonin and dopamine pathways, which may influence pain perception and mood. However, clinical trials specifically examining Vitamin B6 for dysmenorrhea are sparse. Most available research focuses on its use for premenstrual syndrome (PMS) rather than dysmenorrhea itself. Some small studies and anecdotal reports suggest mild benefit, but these are often not well-controlled or adequately powered to draw firm conclusions. Reviews of the literature, such as those by the Cochrane Collaboration, indicate insufficient high-quality evidence to recommend Vitamin B6 as a primary treatment for menstrual pain. Thus, while its use persists in some traditional and complementary medicine circles, mainstream clinical guidelines do not endorse Vitamin B6 for dysmenorrhea due to a lack of convincing scientific validation.

More about Vitamin B6 (pyridoxal 5-phosphate)
More about Dysmenorrhea

Products containing Vitamin B6 (pyridoxal 5-phosphate)

We currently have no products on Vitabase that contain this ingredient.