Evidence supporting the use of: Artichoke
For the health condition: Dyspepsia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Artichoke (Cynara scolymus) leaf extract is used to support and treat dyspepsia, and this use is justified by both traditional and scientific evidence. Traditionally, artichoke leaves have been used in European herbal medicine as a remedy for digestive ailments, including indigestion and dyspepsia. The rationale is based on its cholagogue and choleretic properties—meaning it stimulates bile production and flow, which aids fat digestion and can reduce symptoms like bloating, nausea, and abdominal discomfort.

Scientific validation exists for this traditional use. Several randomized, placebo-controlled clinical trials have evaluated standardized artichoke leaf extract in patients with functional dyspepsia. For example, a double-blind study published in Alimentary Pharmacology & Therapeutics (2003) found significant improvement in dyspeptic symptoms (such as fullness, bloating, and abdominal pain) in patients taking artichoke extract compared to placebo. Other studies, including a large open-label trial in Germany, have reported similar benefits. Meta-analyses and systematic reviews acknowledge modest but consistent improvements in global dyspepsia symptoms.

The proposed mechanisms involve artichoke’s ability to stimulate bile secretion, enhance lipid digestion, and possibly exert antispasmodic and antioxidant effects in the gastrointestinal tract. Though results are generally positive, some studies suggest the effect size is moderate; hence, the evidence is rated as 3 out of 5. Overall, artichoke leaf extract is a well-tolerated option with a reasonable scientific basis for supporting digestive comfort in dyspepsia.

More about artichoke
More about Dyspepsia

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cutch
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green chiretta
apple
artichoke
barberry
basil
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betel
bilberry
black pepper
blackberry
rice
chamomile
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turmeric
curcumin
dandelion
fennel
flavonols
ginger
goldenseal
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licorice root
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mustard seed
oregon grape
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phellodendron amurense
plantain
plum fruit
raspberry
slippery elm bark
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gastrodia
cardamom
papaya
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nut grass
alpinia galangal
Clerodendrum indicum
ferula assafoetida
Hedychium spicatum
anise
Tinospora cordifolia
blackboard tree
Caesalpinia crista
Fumaria parviflora
Swertia
peony
boxthorne
Yarrow
prickly ash
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chrysanthemum
dioscorea
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sweetgums
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indigo leaves
enzymes blend (proprietary)
geranium
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Angelica
Acacia
Agrimony
Achyranthes
Abrus
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asafoetida
Ajuga
Anserina
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Alstonia scholaris
Agrimonia pilosa
Asteraceae
ananain
Abuta
Aniseed myrtle
Arisaema
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bai ji
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blackthorn
bicarbonate
Blepharis
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bistort
Butea monosperma
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bitter grass
bael
Boswellia
banyan
bur-reed
black nightshade
Bombax
bitter principals
black root
banana
Bergenia
Boerhavia diffusa
centaury
Cinnamomum
Combretum quadrangulare
Clerodendrum phlomidis
Centaurium erythraea
citron
carry me seed
capsaicin
curcumen
catechu
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colombo
corktree
Curcuma
chirata
costus
colocynth
Celosia
dianthrone
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Erodium cicutarium
Evodia
elephant\'s head
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Embelia
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four-leaved grass
goldthread
genipap
Gnaphalium
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Gentianella amarella
gallotannin
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Hygrophila
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knotgrass
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luffa
lodhtree
lotus
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little ironweed
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Matico
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Matapalo Tree
Meadow sage
Milkweed
Morning glory
marigold
magnolol
manzanita
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Nimbidin
Oxystelma
Phyllanthus
Premna
Phragmites
Psacalium peltatum
Plantago
Pluchea
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Peucedanum
Portulaca
Plumbago zeylanica
Pimpinella
Patrinia
Physalis angulata
Papayotin
Potentilla
Quisqualis
rue
Rubus
Rubiaceae
Rhus coriaria
Sicklepod
Sophora
Spanish Needle
Salvia
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Snakeroot
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Sagebrush
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Stereospermum
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Servicetree
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Thymus
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