Evidence supporting the use of: Licorice (various)
For the health condition: Dyspepsia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Licorice (Glycyrrhiza glabra and related species) has a long history of use for digestive ailments, including dyspepsia (indigestion). Traditional medicine systems such as Ayurveda, Traditional Chinese Medicine, and European herbal medicine have used licorice for gastrointestinal complaints. Modern scientific research has explored its potential benefits, focusing particularly on deglycyrrhizinated licorice (DGL) extracts, which are modified to reduce glycyrrhizin (a component associated with side effects like hypertension).

Several clinical studies and reviews suggest that DGL may help alleviate symptoms of dyspepsia, such as bloating, discomfort, and nausea, by increasing mucous production and promoting healing of the stomach lining. A small number of randomized controlled trials (RCTs) and observational studies have found that DGL can reduce the severity of functional dyspepsia and even assist in healing minor gastric ulcers, which can present with similar symptoms.

However, while evidence exists supporting licorice’s efficacy in dyspepsia, the quality and quantity of studies are moderate. Most studies are small or have methodological limitations. Nonetheless, the mechanism—primarily mucosal protection rather than acid suppression—has scientific plausibility. Meta-analyses and systematic reviews generally conclude that DGL may offer benefit as an adjunctive therapy for dyspepsia, especially for people who do not tolerate conventional medications. Overall, the use of licorice for dyspepsia is supported by both tradition and some scientific evidence, but more robust clinical trials are needed for definitive recommendations.

More about Licorice (various)
More about Dyspepsia

Other ingredients used for Dyspepsia

cutch
Allspice
Aloe vera
green chiretta
apple
artichoke
barberry
basil
myrobalan
berry flavor
betel
bilberry
black pepper
blackberry
rice
chamomile
Coptis chinensis
turmeric
curcumin
dandelion
fennel
flavonols
ginger
goldenseal
heartwood
Indian tinospora
licorice root
marshmallow
mustard seed
oregon grape
Peppermint
phellodendron amurense
plantain
plum fruit
raspberry
slippery elm bark
sphaeranthus indicus
triphala
gastrodia
cardamom
papaya
Indian bael
neem tree
nut grass
alpinia galangal
clerodendrum indicum
ferula assafoetida
hedychium spicatum
anise
tinospora cordifolia
blackboard tree
caesalpinia crista
fumaria parviflora
swertia
peony
boxthorne
yarrow
prickly ash
myrrh
chrysanthemum
dioscorea
fern
hyacinth bean
sweetgums
morinda
trichosanthes
zanthoxylum
wood betony
white oak
indigo leaves
enzymes blend (proprietary)
geranium
Avens
Angelica
Acacia
Agrimony
Achyranthes
Abrus
Amomum
Asafoetida
Ajuga
Anserina
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Alsonia scholaris
Agrimonia pilosa
Asteracea
Ananain
Abuta
Aniseed myrtle
Arisaema
Black Seed
Bai Ji
Bidens pilosa
Blackthorn
Bicarbonate
Blepharis
Belleric myrobalan
Bistort
Butea monosperma
Barleria
Bitter Grass
Bael
Boswellia
Banyan
Bur-Reed
Black Nightshade
Bombax
Bitter principals
Black root
banana
Bergenia
Boerhavia diffusa
Centaury
Cinnamomum
Combretum quadrangulare
Clerodendrum phlomidis
Centaurium erythraea
Citron
Carry Me Seed
Capsaicin
Curcumen
Catechu
Campylandra fimbriata
Colombo
Corktree
Curcuma
Chirata
Costus
Colocynth
Celosia
Dianthrone
Dichrostachys glomerata
Erodium cicutarium
Evodia
Elephant's Head
European-Five Finger Grass
Embelia
Flueggea suffruticosa
Four leaved grass
Goldthread
Genipap
Gnaphalium
Guava
Gentianella amarella
Gallotannin
Galangal
Hygrophila
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Iridoid glycosides
Indian Coraltree
Long Pepper
Knotgrass
Lebbek
Ledebouriella
Lesser speargrass
Laggera pterodonta
Luffa
Lodhtree
Lotus
Lycopodium
Little ironweed
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Mucilage
Malva sylvestris
Matico
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Matapalo Tree
Meadow sage
Milkweed
Morning Glory
Marigold
Magnolol
Manzanita
Neoandrographolides
Nimbidin
Oxystelma
Phyllanthus
Premna
Phragmites
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Plantago
Pluchea
Pepper Bark Tree
Pentacyclic triterpenoids
Peucedanum
portulaca
Plumbago zeylanica
Pimpinella
Patrinia
Physalis angulata
Papayotin
Potentilla
Quisqualis
Rue
Rubus
Rubiaceae
Rhus coriaria
Sicklepod
Sophora
Spanish Needle
Salvia
Sensitive Plant
Snakeroot
Solanum indicum
Southernwood
Slippery Elm
Sagebrush
Spantholobus
Stereospermum
Sweet Bay
Sandy Everlasting
Servicetree
Sedanenolide
Terminalia
Thymoquinone
Thymus
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Viola
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Yerba buena
Zedoary
Zingerone

Products containing Licorice (various)

We currently have no products on Vitabase that contain this ingredient.