Evidence supporting the use of: Pentacyclic triterpenoids (unspecified)
For the health condition: Dyspepsia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Pentacyclic triterpenoids are a large group of naturally occurring compounds found in many medicinal plants, such as Glycyrrhiza glabra (licorice), Centella asiatica, and Olea europaea (olive). Their use to support or treat dyspepsia (indigestion) is primarily rooted in traditional medicine systems, including Ayurveda, Traditional Chinese Medicine, and European herbal practices. Several plants rich in pentacyclic triterpenoids have a long history of use for various digestive complaints, including dyspepsia. The proposed mechanisms—based on traditional usage and some preliminary pharmacological studies—include anti-inflammatory, gastroprotective, and mild antispasmodic actions that may help relieve symptoms like bloating, discomfort, and mild gastritis.

However, direct scientific validation of pentacyclic triterpenoids as a class for the treatment of dyspepsia is limited. Most available studies focus on individual plant extracts or isolated compounds in preclinical (animal or in vitro) settings, with few well-designed human clinical trials. For example, glycyrrhizin (from licorice) and asiaticoside (from Centella asiatica) have shown some gastroprotective effects in animal models, but this evidence does not robustly translate to clinical efficacy for dyspepsia in humans. As such, the evidence supporting their use for dyspepsia is rated as weak (2/5), and mainly derives from tradition rather than rigorous science.

More about Pentacyclic triterpenoids (unspecified)
More about Dyspepsia

Other ingredients used for Dyspepsia

cutch
allspice
aloe vera
green chiretta
apple
artichoke
barberry
basil
myrobalan
berry flavor
betel
bilberry
black pepper
blackberry
rice
chamomile
Coptis chinensis
turmeric
curcumin
dandelion
fennel
flavonols
ginger
goldenseal
heartwood
Indian tinospora
licorice root
marshmallow
mustard seed
oregon grape
peppermint oil
phellodendron amurense
plantain
plum fruit
raspberry
slippery elm bark
sphaeranthus indicus
triphala
gastrodia
cardamom
papaya
Indian bael
neem tree
nut grass
alpinia galangal
clerodendrum indicum
ferula assafoetida
hedychium spicatum
anise
tinospora cordifolia
blackboard tree
caesalpinia crista
fumaria parviflora
swertia
peony
boxthorne
yarrow
prickly ash
myrrh
chrysanthemum
dioscorea
fern
hyacinth bean
sweetgums
morinda
trichosanthes
zanthoxylum
wood betony
white oak
indigo leaves
enzymes blend (proprietary)
geranium
Avens
Angelica
acacia
Agrimony
Achyranthes
Abrus
Amomum
Asafoetida
Ajuga
Anserina
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Alsonia scholaris
Agrimonia pilosa
Asteracea
Ananain
Abuta
Aniseed myrtle
Arisaema
Black Seed
Bai Ji
Bidens pilosa
Blackthorn
Bicarbonate
Blepharis
Belleric myrobalan
Bistort
Butea monosperma
Barleria
Bitter Grass
Bael
Boswellia
Banyan
Bur-Reed
Black Nightshade
Bombax
Bitter principals
Black root
banana
Bergenia
Boerhavia diffusa
Centaury
Cinnamomum
Combretum quadrangulare
Clerodendrum phlomidis
Centaurium erythraea
Citron
Carry Me Seed
Capsaicin
Curcumen
Catechu
Campylandra fimbriata
Colombo
Corktree
Curcuma
Chirata
Costus
Colocynth
Celosia
Dianthrone
Dichrostachys glomerata
Erodium cicutarium
Elephant's Head
European-Five Finger Grass
Embelia
Goldthread
Galangal
Lotus
Little ironweed
Snakeroot (unspecified)

Products containing Pentacyclic triterpenoids (unspecified)

We currently have no products on Vitabase that contain this ingredient.