Evidence supporting the use of: Peppermint leaf
For the health condition: Dyspepsia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Peppermint Leaf for Dyspepsia: Scientific Evidence

Peppermint leaf (Mentha × piperita) has a long history of use for digestive complaints, but its application in dyspepsia (indigestion) is also supported by modern scientific studies. The primary active constituents in peppermint—menthol and other volatile oils—have demonstrated antispasmodic effects on the smooth muscle of the gastrointestinal tract.

Several randomized controlled trials (RCTs) and meta-analyses have evaluated peppermint oil (often in enteric-coated capsules) for various digestive disorders, including dyspepsia and irritable bowel syndrome (IBS). These studies indicate that peppermint oil can reduce symptoms such as abdominal pain, bloating, and discomfort, which overlap with functional dyspepsia. A 2019 systematic review (Zhang et al.) found peppermint oil to be significantly more effective than placebo for improving global symptoms in functional dyspepsia, although the quality of evidence varies.

The mechanism is believed to involve relaxation of gastrointestinal smooth muscle via calcium channel blockade, reduction of gastric motility, and modulation of visceral sensitivity. However, most research focuses on peppermint oil rather than the dried leaf itself, and studies specifically targeting dyspepsia are fewer than those for IBS.

In summary, the use of peppermint leaf (or more commonly, its oil) for dyspepsia is supported by moderate-quality scientific evidence, though further research would help clarify the optimal form and dosage for this indication.

More about Peppermint leaf
More about Dyspepsia

Other ingredients used for Dyspepsia

cutch
allspice
aloe vera
green chiretta
apple
artichoke
barberry
basil
myrobalan
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betel
bilberry
black pepper
blackberry
rice
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turmeric
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dandelion
fennel
flavonols
ginger
goldenseal
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licorice root
marshmallow
mustard seed
oregon grape
peppermint oil
phellodendron amurense
plantain
plum fruit
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slippery elm bark
sphaeranthus indicus
triphala
gastrodia
cardamom
papaya
Indian bael
neem tree
nut grass
alpinia galangal
clerodendrum indicum
ferula assafoetida
hedychium spicatum
anise
tinospora cordifolia
blackboard tree
caesalpinia crista
fumaria parviflora
swertia
peony
boxthorne
yarrow
prickly ash
myrrh
chrysanthemum
dioscorea
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hyacinth bean
sweetgums
morinda
trichosanthes
zanthoxylum
wood betony
white oak
indigo leaves
enzymes blend (proprietary)
geranium
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Angelica
acacia
Agrimony
Achyranthes
Abrus
Amomum
Asafoetida
Ajuga
Anserina
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Alsonia scholaris
Agrimonia pilosa
Asteracea
Ananain
Abuta
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Arisaema
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Butea monosperma
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banana
Bergenia
Boerhavia diffusa
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Colocynth
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Dichrostachys glomerata
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Products containing Peppermint leaf

We currently have no products on Vitabase that contain this ingredient.