Evidence supporting the use of: Peppermint leaf
For the health condition: Dyspepsia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Peppermint Leaf for Dyspepsia: Scientific Evidence

Peppermint leaf (Mentha × piperita) has a long history of use for digestive complaints, but its application in dyspepsia (indigestion) is also supported by modern scientific studies. The primary active constituents in peppermint—menthol and other volatile oils—have demonstrated antispasmodic effects on the smooth muscle of the gastrointestinal tract.

Several randomized controlled trials (RCTs) and meta-analyses have evaluated peppermint oil (often in enteric-coated capsules) for various digestive disorders, including dyspepsia and irritable bowel syndrome (IBS). These studies indicate that peppermint oil can reduce symptoms such as abdominal pain, bloating, and discomfort, which overlap with functional dyspepsia. A 2019 systematic review (Zhang et al.) found peppermint oil to be significantly more effective than placebo for improving global symptoms in functional dyspepsia, although the quality of evidence varies.

The mechanism is believed to involve relaxation of gastrointestinal smooth muscle via calcium channel blockade, reduction of gastric motility, and modulation of visceral sensitivity. However, most research focuses on peppermint oil rather than the dried leaf itself, and studies specifically targeting dyspepsia are fewer than those for IBS.

In summary, the use of peppermint leaf (or more commonly, its oil) for dyspepsia is supported by moderate-quality scientific evidence, though further research would help clarify the optimal form and dosage for this indication.

More about Peppermint leaf
More about Dyspepsia

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Products containing Peppermint leaf

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