Mouse Ear (Hieracium pilosella), also known as hawkweed, has a long history of use in traditional herbal medicine. It has been employed in European folk remedies for ailments involving the respiratory tract and, less commonly, for ear-related concerns such as earaches or mild ear infections. Preparations were often made into infusions or tinctures and used topically or orally. The traditional rationale was based on the plant's astringent, anti-inflammatory, and mild antimicrobial properties, which were believed to help "dry up" excess fluids and reduce inflammation in mucous membranes, including those connected to the ears via the Eustachian tubes.

However, scientific evidence supporting these uses is minimal. Modern research on Mouse Ear has focused largely on its flavonoid and phenolic content, with some laboratory studies suggesting anti-inflammatory and antibacterial effects. These findings, though promising, have not been directly linked to the treatment or support of ear health in clinical trials. There are no well-designed studies confirming its efficacy for otological (ear) conditions in humans. Consequently, while Mouse Ear continues to be included in some traditional formulas for ear health, its use in this context is supported more by custom and anecdote than by robust scientific validation.