Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactoferrin is a multifunctional glycoprotein found naturally in milk and other secretory fluids. Its proposed use in supporting or treating eczema (atopic dermatitis) is primarily based on its immunomodulatory and anti-inflammatory properties, along with its antimicrobial activity. Several small clinical studies and preclinical investigations suggest that lactoferrin may help reduce inflammation and modulate immune responses, both of which are relevant to the pathophysiology of eczema. For example, a 2019 pilot study found that oral supplementation with lactoferrin led to improvements in atopic dermatitis symptoms in children, though the sample size was small and the study design limited. Other animal and laboratory studies have shown that lactoferrin can influence cytokine production and enhance skin barrier function, which could theoretically benefit eczema patients.

However, high-quality, large-scale randomized controlled trials in humans are lacking, and the evidence remains preliminary. Most mainstream dermatological guidelines do not currently recommend lactoferrin as a standard therapy for eczema. While the biological rationale is plausible and there is early scientific evidence hinting at benefit, more robust research is needed. Thus, the use of lactoferrin for eczema is justified by scientific exploration and early studies, but the strength of evidence is modest at best.

More about Lactoferrin
More about Eczema

Other ingredients used for Eczema

Other health conditions supported by Lactoferrin

Products containing Lactoferrin

Metagenics Probioplex® Intensive Care Powder