Evidence supporting the use of: Marine lipid
For the health condition: Eczema

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Marine lipids, particularly omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been investigated for their potential to support or treat eczema (atopic dermatitis). The theoretical basis for their use lies in their anti-inflammatory properties: omega-3 fatty acids are known to modulate immune responses, reducing the production of pro-inflammatory cytokines and eicosanoids, which are implicated in the pathogenesis of eczema.

Several clinical trials and meta-analyses have explored the efficacy of omega-3 supplementation in eczema. Some small studies have found modest improvements in eczema severity and symptom scores with fish oil or omega-3 supplementation in both adults and children. For example, a 2012 randomized controlled trial published in the British Journal of Dermatology found that supplementation with omega-3 fatty acids resulted in a reduction in eczema severity scores. However, other studies have shown little or no benefit, and the overall quality of evidence is limited by small sample sizes, short durations, and methodological heterogeneity.

Current guidelines do not recommend marine lipids as a first-line therapy for eczema, but they may be considered as adjunctive support in some cases. In summary, there is a scientific rationale and some preliminary clinical evidence supporting the use of marine lipids for eczema, but the strength of evidence is low to moderate (rated 2/5), and more robust, large-scale studies are needed to clarify their efficacy.

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