Casearia esculenta is an herb used in traditional systems of medicine across India, such as Ayurveda and folk medicine, for a variety of ailments, including edema (swelling). The roots and tubers of this plant are believed to possess diuretic properties, which can help remove excess fluid from the body—a common approach in the traditional management of edema. Ethnobotanical surveys have documented its use by indigenous communities to treat swelling and fluid accumulation, and some traditional formulations include Casearia esculenta as an ingredient for this purpose.

However, scientific validation for this use is limited. There are only a handful of preclinical studies exploring the pharmacological activities of Casearia esculenta, and while some animal studies have reported mild diuretic effects, there are no robust clinical trials or comprehensive pharmacological investigations confirming its efficacy or safety for edema in humans. The evidence is thus primarily traditional, supported by ethnomedicinal documentation, rather than modern clinical science.

In summary, while Casearia esculenta has a role in traditional medicine for the management of edema, this use is not well-supported by strong scientific evidence, and it should be approached with caution until more rigorous research is available.