Evidence supporting the use of: Peptidase
For the health condition: Edema
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Peptidases, also known as proteolytic enzymes (such as serrapeptase, nattokinase, and bromelain), have been explored for their potential to support the management of edema, particularly post-surgical or inflammatory edema. The rationale is that these enzymes can help break down proteins in inflammatory exudates and fibrin, which may facilitate the reduction of swelling and improve microcirculation. Several small clinical studies and reviews, particularly in Europe and Japan, have investigated enzymes like serrapeptase and bromelain for their effects on post-operative swelling and localized edema. Some trials report a reduction in swelling and improved recovery times compared to placebo or standard care. However, the quality and size of these studies are limited, and there is variability in study design, dosing, and outcome measures. Systematic reviews generally conclude that while there is some evidence for a mild beneficial effect of peptidases in reducing edema, especially after trauma or surgery, the overall strength of evidence is low to moderate. There is insufficient high-quality, large-scale research to firmly establish their efficacy or safety for general edema, such as that caused by heart, kidney, or liver disease. Therefore, while scientific evidence exists, it is not robust, and peptidases are not widely recommended in mainstream medical guidelines for edema treatment.
Other ingredients used for Edema
anthocyaninsapricot
arjun tree
asparagus
waterhyssop
bamboo
bearberry
bilberry
Indian frankincense
bromelain
bupleurum falcatum
burdock
butcher's broom
bасора
cabbage leaf
celery
chen pi
Chinese salvia root
citrus bioflavonoids
cucumber
turmeric
dandelion
fish protein
flavonols
forsythia
fu ling
gotu kola
greek mountain tea
onion
hawthorn
hesperidin
horse chestnut
horsetail
Japanese sophora
jujube
lemon
lophatherum leaf
lovage
mannitol
moringa
mustard seed
nettle
papain
parsley
pear
pine bark
pineapple
potassium
protease
pumpkin
quercetin
rutin
scrophularia root
serratiopeptidase
specialized pro-resolving mediators (SPMs)
triphala
trypsin
seaweed
watermelon
sarsaparilla
yellow root
tangerine
xanthium (cockleburs)
atractylodes
Indian bael
nut grass
alpinia galangal
punarnava
commiphora
rubia cordifolia
swertia
lingusticum wallichii
goldenrod
prickly ash
lemongrass
silk tree
juniper berries
solomon's seal
siler root
amber
dioscorea
dodder
sweet flag
hyacinth bean
morinda
cornsilk
buchu
birch
couch grass
sheep's sorrel
queen of the meadow
hydrangea
purslane
gentiana macrophylla
cleavers
shepherd's purse
peach
white oak
enzymes blend (proprietary)
Aralia
akebia
Ardisia
Angelica
Agrimony
Achyranthes
Abrus
Albizia
Ajuga
Albumin
Aerva lanata
American Liverleaf
Asam gelugor
Aescin
Adzuki bean
Actaea spicata
Agrimonia pilosa
Arjunic Acid
Alisma
Abuta
Allium tuberosum
Amor seco
Arani
Arisaema
Atractylone
Betony
Baikal Skullcap
Blue Flag
Baliospermum
Blackthorn
Blepharis
Bishop's Weed
Boswellic Acid
Bayleaf
Big Quaking Grass
Bitter Grass
berry
Bogbean
Baccharoides anthelmintica
Banyan
Bioflavonoids
Bombax
Borassus Palm
Borassus aethiopum
Borage
banana
Bupleurum
Baicalin
Bassia scoparia
Black Hellebore
Bergenia
Boerhavia diffusa
Bottle gourd
Borneol
Centella triterpenes
Chinese Silkvine
Casearia esculenta
Chinese Mountain Ant
Calotropis gigantea
Chervil
Clerodendrum trichotomum
Cucurbita
Coriander
Clerodendrum phlomidis
Cactus
Cynomorium
Cinquefoil
Cyathula
Chlorophytum
Curcumen
Centella asiatica
Chanca Piedra
Corktree
Cabbage
Cowslip
Chaenomeles lagenaria
Calamus
Chestnut
Cynodon dactylon
Collinsonia
Carthamus
Celosia
Clerodendrum indicum
Diosmin
Danshen
Deer Root
Dipsacus
Erythropalum scandens
Eupolyphaga sinensis
Empresstree
Echinodorus
Enzyme Blend
European-Five Finger Grass
Escin
Flavonoids
Flavonones
Little ironweed
Rhubarb
Sumac
Zucchini
Other health conditions supported by Peptidase
EdemaInflammation
Injuries
Surgery (healing from)
Wounds and Sores